⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1485914 | 1.00 | — | — | |
| SCHEMBL2209645 | 0.97 | FAAH (0.52) | — | |
| SCHEMBL3128648 | 0.97 | FAAH (0.58) | — | |
| SCHEMBL2137537 | 0.97 | FAAH (0.58) | — | |
| SCHEMBL625642 | 0.97 | FAAH (0.58) | — | |
| SCHEMBL2184557 | 0.97 | FAAH (0.58) | — | |
| SCHEMBL9235251 | 0.97 | FAAH (0.58) | — | |
| SCHEMBL3625233 | 0.97 | FAAH (0.58) | — | |
| SCHEMBL3625235 | 0.97 | FAAH (0.58) | — | |
| SCHEMBL3455495 | 0.97 | FAAH (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215740-A1 | IMMUNOMODULATORY ANTIBODY-DRUG CONJUGATES | SEAGEN INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| US-7789934-B2 | Combination of an N-alkyl- or N,N-dialkylpolyhydroxyalkanamide and a metal soap, an alkylenebisfatty amide, or an N-alkylalkanamide; improves both flowability and lubricity, regardless of a presence or absence of a complicated pretreatment step. | KABUSHIKI KAISHA KOBE SEIKO SHO (JP) | 2010-09-07 | — | — | US | disclosed |
| US-20070154340-A1 | Lubricant for powder metallurgy, powdery mixture for powder metallurgy, and process for producing sinter | KABUSHIKI KAISHA KOBE SEIKO SHO (JP) | 2007-07-05 | — | — | US | disclosed |
| US-7102007-B2 | Dihydroindole and tetrahydroquinoline derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-09-05 | — | — | US | disclosed |
| US-20050020624-A1 | Dihydroindole and tetrahydroquinoline derivatives | AEBI JOHANNES (CH) | 2005-01-27 | — | — | US | disclosed |
| US-6706751-B2 | ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS; ANTIDIABETIC AGENTS; ANTIPROLIFERATIVE AGENTS | HOFFMAN-LA ROCHE INC. | 2004-03-16 | — | — | US | disclosed |
| US-5252675-A | Vulcanized terpolymer of acrylic or methacrylic ester and one monomer selected from a group of maleic anhydride, acids, glycidyl acrylic or methacrylic ester; oil repellents, heat resistance | SHOWA DENKO K.K. (JP) | 1993-10-12 | — | — | US | disclosed |
| US-5093429-A | Multiplex ethylene copolymer, process for preparation thereof and cured product thereof | SHOWA DENKO K.K. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0181408-B1 | MULTI-COMPONENT ETHYLENE COPOLYMERS, PROCESS FOR THEIR PREPARATION, AND VULCANIZATE THEREOF | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-10-24 | — | — | EP | disclosed |
| US-4713489-A | Preparation of N-substituted arylsulfonamides | AKZO AMERICA INC. (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0181408-A1 | MULTI-COMPONENT ETHYLENE COPOLYMERS, PROCESS FOR THEIR PREPARATION, AND VULCANIZATE THEREOF | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1986-05-21 | — | — | EP | disclosed |