Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL18131942 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL693006 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL30350220 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL32679845 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL2335912 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL31633755 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL31413937 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL22686437 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29587574 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1291555 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4132 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122074633-A | Flavour composition, aqueous food composition containing said flavour composition, preparation and use thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122037240-A | High-quality heat-sealing antibacterial modified atmosphere multifunctional fresh-keeping aqueous master batch emulsion and preparation method and application thereof | 广州亿品鲜技术有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-3814303-B1 | NOVEL CROP NUTRITION AND FORTIFICATION COMPOSITION | SML LTD (IN) | 2026-04-29 | — | — | EP | claimed |
| US-20260109622-A1 | LITHIUM NICKEL MANGANESE PHOSPHATE CATHODE MATERIAL AND PREPARATION METHOD THEREOF | HUBEI GAOBO TECH CO LTD (CN) | 2026-04-23 | — | — | US | claimed |
| EP-4729476-A1 | LITHIUM-MANGANESE-IRON-PHOSPHATE POSITIVE ELECTRODE MATERIAL AND PREPARATION METHOD THEREFOR AND LITHIUM-ION BATTERY | Sichuan Tianli Lithium Energy Co., Ltd (CN) | 2026-04-22 | — | — | EP | claimed |
| EP-4724413-A1 | ALPHA ALUMINA-BASED CERAMIC MATERIAL AND METHODS OF MAKING SAME | 3M Innovative Properties Company (US) | 2026-04-15 | — | — | EP | claimed |
| WO-2026044339-A1 | METHODS FOR CAPTURING SULFUR DIOXIDE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2026-03-05 | — | — | WO | claimed |
| US-20260028294-A1 | NOVEL CROP NUTRITION AND FORTIFICATION COMPOSITION | SML LIMITED (IN) | 2026-01-29 | — | — | US | claimed |
| EP-4685871-A1 | PREPARATION METHOD FOR POSITIVE ELECTRODE MATERIAL, POSITIVE ELECTRODE MATERIAL, POSITIVE ELECTRODE SHEET, BATTERY, AND ELECTRIC DEVICE | Jiangsu Contemporary Amperex Technology Limited (CN) | 2026-01-28 | — | — | EP | claimed |
| EP-4682980-A1 | PRECURSOR MATERIAL AND PREPARATION METHOD THEREFOR, POSITIVE ELECTRODE MATERIAL AND PREPARATION METHOD THEREFOR, POSITIVE ELECTRODE SHEET, BATTERY, AND ELECTRIC DEVICE | Jiangsu Contemporary Amperex Technology Limited (CN) | 2026-01-21 | — | — | EP | claimed |
| WO-1998012276-A1 | METHOD FOR MAKING ABRASIVE GRAIN AND ABRASIVE ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-03-26 | — | — | WO | claimed |
| WO-1998008524-A1 | MULTIMINERAL PRODUCTS USEFUL IN ACHIEVING AUTONOMIC BALANCE | GONZALEZ NICHOLAS JAMES (US) | 1998-03-05 | — | — | WO | claimed |
| CN-1171638-A | Positive electrode active material for lithium battery, method for producing same, and lithium battery containing same | JAPAN STORAGE BATTERY CO LTD (JP) | 1998-01-28 | — | — | CN | claimed |
| EP-0813256-A2 | Layered, hexagonal lithium manganese oxide as a positive electrode active material for lithium battery, method for producing the same, and lithium battery containing the same | Japan Storage Battery Company Limited (JP) | 1997-12-17 | — | — | EP | claimed |
| CN-1148738-A | Positive-pole active material for lithium cell and making method thereof | JAPANESE CELL CO LTD (JP) | 1997-04-30 | — | — | CN | claimed |
| CN-1134407-A | Composition for fertilizer | JAPAN METALS & CHEM CO LTD (JP) | 1996-10-30 | — | — | CN | claimed |
| EP-0712173-A1 | Positive electrode active material for nonaqueous cell and its process of preparation | Japan Storage Battery Co., Ltd. (JP) | 1996-05-15 | — | — | EP | claimed |
| WO-1995019178-A1 | METHODS AND COMPOSITIONS FOR TREATMENT AND DIAGNOSIS OF ALZHEIMER DISEASE AND OTHER DISORDERS | RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. (US) | 1995-07-20 | — | — | WO | claimed |
| CN-1073841-A | Compound salt with nutrition and health function and preparation method thereof | NIE JINGMIN (CN) | 1993-07-07 | — | — | CN | claimed |
| US-4546068-A | AROMATIC AMINE DEVELOPER, MANANESE AND OR CERIUM SALT, DIPHOSPHONIC ACID SEQUESTERING AGENT | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-10-08 | — | — | US | claimed |