SCHEMBL362834

SCHEMBL362834

CC(C)(C(=O)O)C(=O)CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.42
SRR Q9GZT4 1/20 0.42
TSHR P16473 2/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42
ALDH1A1 P00352 2/20 0.38
HMGCR P04035 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
NAALAD2 Q9Y3Q0 1/20 0.37
FFAR3 O14843 1/20 0.33
KDM4E B2RXH2 1/20 0.32
FFAR1 O14842 1/20 0.32
CPT2 P23786 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM4C Q9H3R0 1/20 0.31
ACLY P53396 2/20 0.31
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL5568061 0.82 LDHA (0.56) LDHASRRTSHRCYP2D6CYP2C19
SCHEMBL42256 0.81 TSHR (0.36) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL4841368 0.81 KDM4E (0.37) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL768330 0.79 TSHR (0.35) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL5014188 0.79 TSHR (0.35) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL6205755 0.79 FFAR3 (0.43) LDHASRRTSHRCYP2D6CYP2C19
SCHEMBL5974062 0.79 TSHR (0.35) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL8981788 0.79 TSHR (0.35) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL7629526 0.79 TSHR (0.35) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL6861198 0.79 TSHR (0.35) TSHRCYP2D6CYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4171806-B1 TRIMETALLIC CATALYST MADE FROM NICKEL, MOLYBDENUM AND TUNGSTEN AND USE THEREOF IN A HYDROTREATMENT AND/OR HYDROCRACKING PROCESS IFP ENERGIES NOW (FR) 2024-05-15 EP claimed
EP-3218010-B1 POLYMER COMPOSED OF REPEAT UNITS HAVING A BIOLOGICALLY ACTIVE MOLECULE ATTACHED THERETO VIA A PH-SENSITIVE BOND SPIREA LTD (GB) 2022-10-26 EP claimed
US-11020408-B2 Polymer composed of repeat units having a biologically active molecule attached thereto via a pH-sensitive bond SPIREA LIMITED (GB) 2021-06-01 US claimed
EP-2496649-B2 FILM-FORMING COMPOSITION CONTAINING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE SAINT GOBAIN ADFORS (FR) 2020-10-28 EP claimed
US-20200289531-A1 POLYMER COMPOSED OF REPEAT UNITS HAVING A BIOLOGICALLY ACTIVE MOLECULE ATTACHED THERETO VIA A PH-SENSITIVE BOND SPIREA LIMITED (GB) 2020-09-17 US claimed
US-10709717-B2 Polymer composed of repeat units having a biologically active molecule attached thereto via a pH-sensitive bond SPIREA LIMITED (GB) 2020-07-14 US claimed
EP-3491064-A1 POLYMER DISPERSIONS WITH REDUCED EMISSION OF ACETALDEHYDE Stahl International B.V. (NL) 2019-06-05 EP claimed
EP-2268589-B1 SIZING COMPOSITION FOR MINERAL FIBERS AND RESULTING PRODUCTS SAINT GOBAIN ISOVER (FR) 2018-06-13 EP claimed
WO-2018024559-A1 POLYMER DISPERSIONS WITH REDUCED EMISSION OF ACETALDEHYDE BASF SE (DE) 2018-02-08 WO claimed
EP-2438025-B1 MINERAL FIBER MAT CONTAINING A FORMALDEHYDE-TRAPPING AGENT, AND METHODS FOR MANUFACTURING SAME SAINT-GOBAIN ADFORS (FR) 2017-12-27 EP claimed
WO-2009136105-A2 SIZING COMPOSITION FOR MINERAL FIBERS AND RESULTING PRODUCTS SAINT-GOBAIN ISOVER (FR) 2009-11-12 WO claimed
US-20090258042-A1 Encapsulated Active Materials Containing Adjunct Crosslinkers INTERNATIONAL FLAVORS & FRAGRANCES INC. 2009-10-15 US claimed
WO-2009103615-A1 IMPROVEMENTS RELATING TO BENEFIT PARTICLES UNILEVER PLC (GB) 2009-08-27 WO claimed
US-20070138671-A1 Encapsulated active material with reduced formaldehyde potential INTERNATIONAL FLAVORS & FRAGRANCES INC. 2007-06-21 US claimed
US-20070138674-A1 ENCAPSULATED ACTIVE MATERIAL WITH REDUCED FORMALDEHYDE POTENTIAL INTERNATIONAL FLAVORS & FRAGRANCES INC. 2007-06-21 US claimed
EP-1797947-A2 Encapsulated active material with reduced formaldehyde potential INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) 2007-06-20 EP claimed
EP-0739199-B1 ESTRADIOL PENETRATION INTENSIFIER FOR TRANSDERMAL ADMINISTRATION LOHMANN THERAPIE SYST LTS (DE) 2002-04-03 EP claimed
US-6090404-A SUSTAINED RELEASE PATCH LTS LOHMANN THERAPIE-SYSTEME GMBH (DE) 2000-07-18 US claimed
EP-0739199-A1 ESTRADIOL PENETRATION INTENSIFIER FOR TRANSDERMAL ADMINISTRATION LTS LOHMANN Therapie-Systeme GmbH (DE) 1996-10-30 EP claimed
WO-1995019162-A1 ESTRADIOL PENETRATION INTENSIFIER FOR TRANSDERMAL ADMINISTRATION LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. KG (DE) 1995-07-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11020408-B2 Polymer composed of repeat units having a biologically active molecule attached thereto via a pH-sensitive bond IL1R1, SRRM2, H1-2 LDHA 1008/4885SRR 111/4885TSHR 372/4885
US-20200289531-A1 POLYMER COMPOSED OF REPEAT UNITS HAVING A BIOLOGICALLY ACTIVE MOLECULE ATTACHED THERETO VIA A PH-SENSITIVE BOND IL1R1, SRRM2, H1-2 LDHA 1008/4885SRR 111/4885TSHR 372/4885
US-10709717-B2 Polymer composed of repeat units having a biologically active molecule attached thereto via a pH-sensitive bond IL1R1, SRRM2, H1-2 LDHA 1008/4885SRR 111/4885TSHR 372/4885
US-20090258042-A1 Encapsulated Active Materials Containing Adjunct Crosslinkers CAPG, ANXA5, CD68 LDHA 583/4885SRR 4219/4885TSHR 4750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.