Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 18/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182187 | 0.85 | SLC6A7 (0.72) | SLC6A7SLC6A3ALDH1A1TSHRKDM4E | |
| SCHEMBL3586157 | 0.82 | SLC6A7 (1.00) | SLC6A7SLC6A3ALDH1A1TSHR | |
| SCHEMBL4789639 | 0.82 | SLC6A7 (0.68) | SLC6A7SLC6A3ALDH1A1TSHRKDM4E | |
| SCHEMBL3823144 | 0.81 | SLC6A7 (0.76) | SLC6A7SLC6A3ALDH1A1TSHRKDM4E | |
| SCHEMBL3576489 | 0.80 | SLC6A7 (1.00) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3585585 | 0.80 | SLC6A7 (1.00) | SLC6A7SLC6A3ALDH1A1TSHRKDM4E | |
| SCHEMBL3578242 | 0.80 | SLC6A7 (1.00) | SLC6A7SLC6A3ALDH1A1TSHRKDM4E | |
| SCHEMBL3585906 | 0.79 | SLC6A7 (0.77) | SLC6A7SLC6A3ALDH1A1TSHRKDM4E | |
| SCHEMBL4391715 | 0.78 | SLC6A7 (0.90) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3583123 | 0.78 | SLC6A7 (1.00) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081691-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF THEIR USE | LEXICON PHARMACEUTICALS, INC. (US) | 2010-04-01 | — | — | US | disclosed |
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081691-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF THEIR USE | GRIN2C, CHAT, COMT | SLC6A7 1113/4885SLC6A3 134/4885ALDH1A1 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.