SCHEMBL3628405

SCHEMBL3628405

O=C(O)Oc1ccc2c(OC(=O)O)cc(OC(=O)O)cc2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.42
MAPT P10636 5/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
TTR P02766 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
FLT3 P36888 1/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
ELANE P08246 3/20 0.35
ACHE P22303 1/20 0.34
GLA P06280 1/20 0.34
GAA P10253 1/20 0.34
MMP1 P03956 1/20 0.33
MMP12 P39900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15103581 0.84 ALDH1A1 (0.44) KDM4EMAPTMEN1KMT2ATDP1
SCHEMBL9785353 0.82 KMT2A (0.45) KDM4EMAPTMEN1KMT2ATDP1
SCHEMBL9485691 0.80 KMT2A (0.48) KDM4EMAPTMEN1KMT2ATDP1
SCHEMBL8030911 0.80 KDM4E (0.37) KDM4EMAPTMAPK1LMNATP53
SCHEMBL809274 0.80 KMT2A (0.55) KDM4EMAPTMEN1KMT2ATDP1
SCHEMBL9647188 0.79 KMT2A (0.47) KDM4EMAPTMEN1KMT2ATDP1
SCHEMBL5678543 0.79 KDM4E (0.46) KDM4EMAPTMEN1KMT2ATDP1
SCHEMBL686585 0.78 KDM4E (0.48) KDM4EMAPTMEN1KMT2ATDP1
SCHEMBL1551903 0.77 KDM4E (0.44) KDM4EMAPTMEN1KMT2ATDP1
SCHEMBL8722118 0.76 KDM4E (0.47) KDM4EMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541030-A ELECTROSTATIC LATENT IMAGES MINOLTA CO., LTD. (JP) 1996-07-30 US claimed
EP-1239335-B1 Method of developing a latent electrostatic image with a two component developer RICOH CO LTD (JP) 2014-06-25 EP disclosed
US-7725057-B2 Image forming method and image forming apparatus KYOCERA MITA CORPORATION (JP) 2010-05-25 US disclosed
US-20070231019-A1 Image forming method and image forming apparatus KYOCERA MITA CORPORATION (JP) 2007-10-04 US disclosed
US-6696213-B2 USING A TWO-COMPONENT DEVELOPER SYSTEM RICOH COMPANY, LTD. (JP) 2004-02-24 US disclosed
US-20030044713-A1 Method of developing a latent electrostatic image RICOH COMPANY LTD (JP) 2003-03-06 US disclosed
EP-1239335-A1 Method of developing a latent electrostatic image with a two component developer Ricoh Company (JP) 2002-09-11 EP disclosed
US-5541030-A ELECTROSTATIC LATENT IMAGES MINOLTA CO., LTD. (JP) 1996-07-30 US disclosed