SCHEMBL3628614

SCHEMBL3628614

CCCCCCCCC(CC)C(N)=O

nearest known ligand 0.83

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.83
CA1 P00915 4/20 0.83
MAPK1 P28482 1/20 0.54
GRIK1 P39086 2/20 0.52
GRIK2 Q13002 2/20 0.52
SLC1A2 P43004 1/20 0.48
SLC1A1 P43005 1/20 0.48
GPR84 Q9NQS5 4/20 0.47
FFAR1 O14842 1/20 0.47
EPHX1 P07099 1/20 0.46
MAPT P10636 1/20 0.45
LCK P06239 1/20 0.45
PPARD Q03181 1/20 0.45
ZDHHC20 Q5W0Z9 1/20 0.45
ZDHHC2 Q9UIJ5 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4616998 1.00 CA2 (0.83) CA2CA1MAPK1GRIK1GRIK2
SCHEMBL28237938 1.00 CA2 (0.83) CA2CA1MAPK1GRIK1GRIK2
SCHEMBL1665997 1.00 CA2 (0.83) CA2CA1MAPK1GRIK1GRIK2
SCHEMBL28156543 1.00 CA2 (0.83) CA2CA1MAPK1GRIK1GRIK2
SCHEMBL1668977 1.00 CA2 (0.83) CA2CA1MAPK1GRIK1GRIK2
SCHEMBL5090059 1.00 CA2 (0.83) CA2CA1MAPK1GRIK1GRIK2
SCHEMBL3859929 1.00 CA2 (0.83) CA2CA1MAPK1GRIK1GRIK2
SCHEMBL6119566 1.00 CA2 (0.83) CA2CA1MAPK1GRIK1GRIK2
SCHEMBL10706703 1.00 CA2 (0.83) CA2CA1MAPK1GRIK1GRIK2
Hydrochloric Acid SCHEMBL22235759 0.98 CA2 (0.80) CA2CA1MAPK1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111936144-B JAK inhibitors 廖细斌 2023-12-22 CN claimed
CN-116648451-A Antagonist compounds 阿道尔克斯治疗有限公司 2023-08-25 CN claimed
CN-111936144-A JAK inhibitors 廖细斌 2020-11-13 CN claimed
CN-102365276-A Substituted spiro-amide compounds GRUENENTHAL GMBH 2012-02-29 CN claimed
US-20250243187-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-07-31 US disclosed
CN-118234731-A RAS inhibitors 锐新医药公司 2024-06-21 CN disclosed
CN-118206550-A SHP2 inhibitor and application thereof 江苏威凯尔医药科技有限公司 2024-06-18 CN disclosed
CN-118159548-A Antiviral compounds 安力高医药股份有限公司 2024-06-07 CN disclosed
CN-118103074-A Cytotoxic targeting chimeras for CCR2 expressing cells 葛兰素史克知识产权发展有限公司 2024-05-28 CN disclosed
US-11952352-B2 Ras inhibitors Revolution Medicines, Inc. (US) 2024-04-09 US disclosed
US-20240109871-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-04-04 US disclosed
CN-117715658-A Method for inhibiting RAS 锐新医药公司 2024-03-15 CN disclosed
CN-111886229-A Herbicidal compounds 先正达参股股份有限公司 2020-11-03 CN disclosed
CN-109789066-A Drug and make-up composition containing resorcinol derivatives 西姆莱斯股份公司 2019-05-21 CN disclosed
CN-109641025-A Medicine containing ginger root CO2 extract 西姆莱斯股份公司 2019-04-16 CN disclosed
CN-109562046-A Cosmetic composition containing sclareolide 西姆莱斯股份公司 2019-04-02 CN disclosed
CN-109475482-A Drug 西姆莱斯股份公司 2019-03-15 CN disclosed
CN-107459473-B A kind of methionine derivative corrosion inhibiter and its synthetic method for pickling iron and steel 唐山学院 2019-02-01 CN disclosed
CN-102365276-A Substituted spiro-amide compounds GRUENENTHAL GMBH 2012-02-29 CN disclosed
WO-2010151815-A2 3,9-DIAZASPIRO[5,5]UNDECANE AMIDES AND UREAS AND METHODS OF USE THEREOF ABBOTT LABORATORIES (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243187-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 CA2 2999/4885CA1 4151/4885MAPK1 1561/4885
US-20240109871-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 CA2 2999/4885CA1 4151/4885MAPK1 1561/4885
US-11952352-B2 Ras inhibitors KRAS, NRAS, HRAS CA2 3819/4885CA1 4685/4885MAPK1 352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.