Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 3/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630125 | 0.86 | SMN1; SMN2 (0.44) | ACKR3HSD11B1ALDH1A1POLBMGLL | |
| SCHEMBL311627 | 0.86 | KMT2A (0.50) | KMT2AACKR3TSHRLMNAKDM4E | |
| SCHEMBL311246 | 0.85 | STS (0.56) | KMT2AACKR3KDM4EHSD11B1UBE2M | |
| SCHEMBL805657 | 0.84 | RXFP1 (0.51) | ACKR3LMNAALDH1A1POLBCCR2 | |
| SCHEMBL13006887 | 0.72 | NR1H4 (0.52) | KMT2ATSHRLMNAALDH1A1MEN1 | |
| SCHEMBL311411 | 0.72 | KMT2A (0.55) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL14608979 | 0.72 | CCR2 (0.45) | LMNAALDH1A1MGLLCCR2 | |
| SCHEMBL5202821 | 0.72 | CCR2 (0.45) | LMNAALDH1A1MGLLCCR2 | |
| SCHEMBL311785 | 0.72 | EPHX2 (0.52) | KMT2AKDM4EHSD11B1MGLLMEN1 | |
| SCHEMBL15732567 | 0.71 | GAA (0.50) | KMT2ALMNAHSD11B1UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148880-A1 | P70 S6 KINASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008140947-A1 | P70 S6 KINASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2008-11-20 | — | — | WO | disclosed |