SCHEMBL3628703

SCHEMBL3628703

C[SiH](O)CCCOCC1CO1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.58
ALDH1A1 P00352 5/20 0.55
TDP1 Q9NUW8 1/20 0.55
MAPK1 P28482 1/20 0.41
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
PDK1 Q15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16901523 1.00 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL18873519 0.95 TSHR (0.64) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4359009 0.85 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL15417623 0.82 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL25275038 0.81 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL5604343 0.81 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL12203029 0.81 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL15763292 0.81 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28525819 0.81 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL642389 0.80 TSHR (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116216931-B Preparation method and application of denitrification solid slow-release carbon source 中国科学院南京地理与湖泊研究所 2024-08-20 CN claimed
CN-116216931-A Preparation method and application of denitrification solid slow-release carbon source 中国科学院南京地理与湖泊研究所 2023-06-06 CN claimed
CN-116216931-B Preparation method and application of denitrification solid slow-release carbon source 中国科学院南京地理与湖泊研究所 2024-08-20 CN disclosed
CN-116216931-A Preparation method and application of denitrification solid slow-release carbon source 中国科学院南京地理与湖泊研究所 2023-06-06 CN disclosed
US-11225600-B2 Modified reactive resin compositions and use thereof for coating propping agents WACKER CHEMIE AG (DE) 2022-01-18 US disclosed
US-11078410-B2 Modified reactive resin compositions and use thereof for coating propping agents WACKER CHEMIE AG (DE) 2021-08-03 US disclosed
US-20210207022-A1 MODIFIED REACTIVE RESIN COMPOSITIONS AND USE THEREOF FOR COATING PROPPING AGENTS WACKER CHEMIE AG (DE) 2021-07-08 US disclosed
US-20190233720-A1 METHOD FOR COATING PROPPANTS WACKER CHEMIE AG (DE) 2019-08-01 US disclosed
US-20190023980-A1 MODIFIED REACTIVE RESIN COMPOSITIONS AND USE THEREOF FOR COATING PROPPING AGENTS WACKER CHEMIE AG (DE) 2019-01-24 US disclosed
US-20170277002-A1 WAVELENGTH CONVERSION MEMBER, BACKLIGHT UNIT, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-09-28 US disclosed
EP-3081586-A1 METHOD FOR MODIFYING SURFACE AND SURFACE MODIFIED ELASTIC BODY Sumitomo Rubber Industries, Ltd. (JP) 2016-10-19 EP disclosed
WO-2001085864-A1 SILICONE/ADHESIVE COMPLEX WHEREOF THE INTERFACE HAS A RELEASE FORCE CAPABLE OF BEING MODULATED BY ELECTRON BEAM IRRADIATION RHODIA CHIMIE (FR) 2001-11-15 WO disclosed
WO-2001030931-A1 ANTI-ADHERENT SILICONE/ADHESIVE COMPLEX WITH STABILISING ADDITIVE RHODIA CHIMIE (FR) 2001-05-03 WO disclosed
EP-0907685-A1 USE OF PLATINUM COMPLEXES PARTICULARLY AS HOMOGENEOUS AND HEAT ACTIVABLE CATALYSTS FOR HYDROSILYLATION RHODIA CHIMIE (FR) 1999-04-14 EP disclosed
US-5795947-A RELEASE PAPER COATINGS RHONE-POULENC CHIMIE (FR) 1998-08-18 US disclosed
WO-1998000463-A1 USE OF PLATINUM COMPLEXES PARTICULARLY AS HOMOGENEOUS AND HEAT ACTIVABLE CATALYSTS FOR HYDROSILYLATION RHODIA CHIMIE (FR) 1998-01-08 WO disclosed
EP-0750623-A1 PLATINUM COMPLEXES AND LIGHT-ACTIVATABLE HYDROSILYLATION CATALYSTS CONTAINING SAME RHONE-POULENC CHIMIE (FR) 1997-01-02 EP disclosed
US-5466746-A Emulsions of organopolysiloxanes containing polar groups with alkyl polyglycosides as emulsifiers WACKER-CHEMIE GMBH (DE) 1995-11-14 US disclosed
WO-1995025734-A1 PLATINUM COMPLEXES AND LIGHT-ACTIVATABLE HYDROSILYLATION CATALYSTS CONTAINING SAME RHONE POULENC CHIMIE (FR) 1995-09-28 WO disclosed
EP-0632085-A1 Silicone polymers having olefinic functional groups, process for their preparation, and curable compositions comprising them RHONE-POULENC CHIMIE (FR) 1995-01-04 EP disclosed