SCHEMBL4359009

SCHEMBL4359009

C[SiH](C)CCCOCC1CO1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
SMN1; SMN2 Q16637 1/20 0.62
ALDH1A1 P00352 6/20 0.58
TDP1 Q9NUW8 1/20 0.58
MAPK1 P28482 1/20 0.44
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GLA P06280 1/20 0.31
PDK1 Q15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28411919 0.94 TSHR (0.69) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL9392314 0.92 TSHR (0.67) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL16901523 0.85 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28525819 0.85 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL3628703 0.85 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL25275038 0.85 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL5604343 0.85 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL12203029 0.85 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL15763292 0.85 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL642389 0.83 TSHR (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103937168-A Underfill for high density interconnect flip chips NAMICS CORP 2014-07-23 CN claimed
CN-102712740-A Underfill for High Density Interconnect Flip Chip NAMICS CORP 2012-10-03 CN claimed
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed
CN-107428074-B Crosslinkable silicone composition for producing highly transparent moldings by the ballistic method 瓦克化学股份公司 2019-11-26 CN disclosed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US disclosed
US-20170159039-A1 HIGH LOAD ENZYME IMMOBILIZATION BY CROSSLINKING ROCHE DIABETES CARE GMBH (DE) 2017-06-08 US disclosed
US-9644057-B2 Resin composition and method for manufacturing the same PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2017-05-09 US disclosed
US-20170108792-A1 LIQUID ELECTROPHOTOGRAPHIC VARNISH COMPOSITION HP INDIGO B.V. (NL) 2017-04-20 US disclosed
CN-103937168-B Underfill for high density interconnect flip chips 纳美仕有限公司 2017-04-12 CN disclosed
US-7592399-B2 vinyldimethylsiloxy-end-capped dimethylsiloxane-diphenylsiloxane copolymer; methylhydrogenpolysiloxane; 2-ethylhexyl alcohol-modified chloroplatinic acid catalyst; hydrogenated bisphenol A modified with substituted or unsubstituted hydrocarbon groups or silyl groups; an aluminum base curing catalyst SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-09-22 US disclosed
CN-101483171-A Airgap-containing interconnect structure with patternable low-K material and method of fabricating IBM (US) 2009-07-15 CN disclosed
US-7319129-B2 Silsesquioxane derivative and process for producing the same CHISSO CORPORATION (JP) 2008-01-15 US disclosed
US-20070142574-A1 vinyldimethylsiloxy-end-capped dimethylsiloxane-diphenylsiloxane copolymer; methylhydrogenpolysiloxane; 2-ethylhexyl alcohol-modified chloroplatinic acid catalyst; hydrogenated bisphenol A modified with substituted or unsubstituted hydrocarbon groups or silyl groups; an aluminum base curing catalyst SHIN-ETSU CHEMICAL CO., LTD. 2007-06-21 US disclosed
US-20070090052-A1 Chromatographic stationary phase AGILENT TECHNOLOGIES, INC. 2007-04-26 US disclosed
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance CHISSO CORPORATION (JP) 2006-03-09 US disclosed
EP-0967237-B1 SILICONE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME NIPPON STEEL CHEMICAL CO (JP) 2003-10-01 EP disclosed
US-6284858-B1 Silicone compounds and process for producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2001-09-04 US disclosed
EP-0967237-A1 SILICONE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME Nippon Steel Chemical Co., Ltd. (JP) 1999-12-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance STS, PFAS, POLQ TSHR 2188/4885SMN1; SMN2 4297/4885ALDH1A1 2132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.