Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297948 | 0.81 | DNMT3A (0.55) | HDAC8DNMT3AHPGDHSD17B10MEN1 | |
| SCHEMBL5407954 | 0.78 | HDAC8 (0.51) | HDAC8DNMT3AHPGDHSD17B10MEN1 | |
| SCHEMBL27846962 | 0.75 | HDAC8 (0.53) | HDAC8DNMT3AHPGDHSD17B10MEN1 | |
| SCHEMBL4558108 | 0.74 | ASAH1 (0.50) | HDAC8DNMT3AHPGDHSD17B10MEN1 | |
| SCHEMBL3795625 | 0.74 | HDAC8 (0.55) | HDAC8DNMT3AHPGDHSD17B10MEN1 | |
| SCHEMBL11586380 | 0.73 | KMT2A (0.55) | HDAC8DNMT3AHPGDHSD17B10MEN1 | |
| SCHEMBL14740086 | 0.72 | HSD17B10 (0.54) | HDAC8DNMT3AHPGDHSD17B10MEN1 | |
| SCHEMBL5089332 | 0.72 | MEN1 (0.54) | HDAC8DNMT3AHPGDHSD17B10MEN1 | |
| SCHEMBL8871621 | 0.72 | MEN1 (0.54) | HDAC8DNMT3AHPGDHSD17B10MEN1 | |
| SCHEMBL433631 | 0.72 | HDAC8 (0.44) | HDAC8DNMT3AHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398576-A1 | HYDROPHILIC POROUS SUBSTRATES | 3M Innovative Properties Company (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096429-A1 | HYDROPHILIC POROUS SUBSTRATES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-08-26 | — | — | WO | disclosed |
| US-6590094-B2 | Methacrylate resin for use as tool in genetic analysis | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-08 | — | — | US | disclosed |
| US-20020106659-A1 | Methacrylate resin for use as tool in genetic analysis | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-08 | — | — | US | disclosed |