Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3629373 | 1.00 | GAA (0.44) | GAAKDM4EALDH1A1MAPTRXFP1 | |
| SCHEMBL15739724 | 0.89 | KDM4E (0.46) | GAAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL3631687 | 0.87 | MAPK8 (0.41) | GAAKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL3631690 | 0.87 | MAPK8 (0.41) | GAAKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL1937259 | 0.82 | GAA (0.37) | GAAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL1937258 | 0.82 | GAA (0.37) | GAAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL3627940 | 0.81 | GPR65 (0.40) | GAAKDM4EALDH1A1MAPTRXFP1 | |
| SCHEMBL3627945 | 0.81 | GPR65 (0.40) | GAAKDM4EALDH1A1MAPTRXFP1 | |
| SCHEMBL3627682 | 0.80 | GAA (0.49) | GAAKDM4EALDH1A1MAPTRXFP1 | |
| SCHEMBL3627678 | 0.80 | GAA (0.49) | GAAKDM4EALDH1A1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010032875-A2 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2010-03-25 | — | — | WO | disclosed |