Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3623040 | 0.89 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL1477898 | 0.83 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL11245362 | 0.80 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL3294367 | 0.80 | TSHR (0.41) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL17851223 | 0.78 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL17851225 | 0.78 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL17851218 | 0.78 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21560994 | 0.78 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL17851224 | 0.78 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL17851221 | 0.78 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260612-B2 | Antistatic article, method of making the same, and display device having the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-02-16 | — | — | US | disclosed |
| EP-2178998-B1 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2014-03-05 | — | — | EP | disclosed |
| US-20130236702-A1 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-09-12 | — | — | US | disclosed |
| US-8449970-B2 | Antistatic article, method of making the same, and display device having the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-28 | — | — | US | disclosed |
| EP-2178998-A2 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M Innovative Properties Company (US) | 2010-04-28 | — | — | EP | disclosed |
| US-20090029129-A1 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-29 | — | — | US | disclosed |
| WO-2009014897-A2 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-01-29 | — | — | WO | disclosed |