SCHEMBL3294367

SCHEMBL3294367

C=CC(=O)OCCC(CCCS(=O)(=O)O)N(C)C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.41
HPGD P15428 1/20 0.41
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 2/20 0.41
TP53 P04637 3/20 0.38
HIF1A Q16665 3/20 0.38
HSD17B10 Q99714 1/20 0.38
THRB P10828 2/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1726114 0.87 TSHR (0.44) TSHRHPGDALDH1A1CYP3A4TP53
Bromide SCHEMBL3630569 0.80 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL8177305 0.78 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4TP53
Bromide SCHEMBL3623040 0.78 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1477898 0.77 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL14882 0.77 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27971941 0.75 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29966916 0.75 TSHR (0.32) TSHRHPGDALDH1A1CYP3A4
SCHEMBL316981 0.75 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL2457988 0.75 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675880-B1 METHOD FOR PARTIAL OR TOTAL OXIDATION OF ONE OR SEVERAL THIOCARBONYLTHIO ENDS OF A POLYMER OBTAINED BY RADICAL POLYMERISATION CONTROLLED BY REVERSIBLE ADDITION-CLEAVAGE RHODIA CHIMIE SA (FR) 2019-03-13 EP claimed
US-7728088-B2 Synthesis of statistical microgels by means of controlled radical polymerisation RHODIA OPERATIONS (FR) 2010-06-01 US claimed
US-7473740-B2 Oxidizing one or more thiocarbonylthio ends of a polymer resulting from a radical polymerization controlled by reversible addition-fragmentation using thiocarbonylthio by reacting with ozone RHODIA CHIMIE (FR) 2009-01-06 US claimed
US-20070027266-A1 Oxidizing one or more thiocarbonylthio ends of a polymer resulting from a radical polymerization controlled by reversible addition-fragmentation using thiocarbonylthio by reacting with ozone SPECIALTY OPERATIONS FRANCE (FR) 2007-02-01 US claimed
US-20060106178-A1 Synthesis of statistical microgels by means of controlled radical polymerisation RHODIA CHIMIE (FR) 2006-05-18 US claimed
EP-1278809-B1 SILICONE/ADHESIVE COMPLEX WHEREOF THE INTERFACE HAS A RELEASE FORCE CAPABLE OF BEING MODULATED BY ELECTRON BEAM IRRADIATION RHODIA CHIMIE SA (FR) 2005-11-09 EP claimed
EP-1242552-B1 CATION-CURABLE SILICONE /ADHESIVE COMPLEX WHEREOF THE INTERFACE HAS RELEASE FORCE CAPABLE OF BEING MODULATED RHODIA CHIMIE SA (FR) 2005-02-09 EP claimed
EP-1123360-B1 COATING COMPOSITIONS CONTAINING FUNCTIONALISED SILICONES RHODIA CHIMIE SA (FR) 2004-12-15 EP claimed
EP-1040142-B1 USE OF AN AQUEOUS PRESSURE SENSITIVE ADHESIVE (PSA) EMULSION, WITH HIGH SHEARING RESISTANCE RHODIA CHIMIE SA (FR) 2004-06-23 EP claimed
US-20030186013-A1 Silicone/adhesive complex whereof the interface has a release force capable of being modulated by electron beam irradiation RHODIA CHIMIE (FR) 2003-10-02 US claimed
US-6590026-B1 Epoxyfunctionalized polysiloxane emulsion, latex, and mineral filler; paints, coatings RHODIA CHIMIE (FR) 2003-07-08 US claimed
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof BOSTIK SA (FR) 2023-12-05 US disclosed
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF UNIVERSITE DE RENNES (FR) 2021-06-17 US disclosed
EP-1490411-B1 METHOD FOR CONTROLLING THE STABILITY OF EMULSIONS AND STABILIZED EMULSIONS RHODIA CHIMIE SA (FR) 2009-01-21 EP disclosed
US-7473740-B2 Oxidizing one or more thiocarbonylthio ends of a polymer resulting from a radical polymerization controlled by reversible addition-fragmentation using thiocarbonylthio by reacting with ozone RHODIA CHIMIE (FR) 2009-01-06 US disclosed
CN-1216052-A Composite particles including organic polymer and oxide and/or hydroxide RHODIA CHIMIE SA (FR) 1999-05-05 CN disclosed
US-5756210-A USE AS FILLERS OR ADDITIVES IN PLASTICS AND ELASTOMERS RHONE-POULENC CHIMIE (FR) 1998-05-26 US disclosed
US-5721026-A CATIONIC OR NONIONIC SURFACTANT STABILIZERS; CROSSLINKING AGENT; NONSILICEOUS FILLER MATERIAL RHONE-POULENC CHIMIE (FR) 1998-02-24 US disclosed
US-5395903-A Conjugated diene chain-transfer agents for polymerization of olefinically unsaturated (co)monomers RHONE-POULENC CHIMIE (FR) 1995-03-07 US disclosed
US-5360851-A Seals and molding materials RHONE-POULENC CHIMIE (FR) 1994-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof MEP1A, MEP1B, ALOX5 TSHR 4885/4885HPGD 278/4885ALDH1A1 581/4885
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF MEP1A, MEP1B, ALOX5 TSHR 4885/4885HPGD 278/4885ALDH1A1 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.