SCHEMBL3630698

SCHEMBL3630698

CCc1cccc(C2C(=O)NC(=O)NC2=O)c1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.42
CRBN Q96SW2 1/20 0.42
MGLL Q99685 2/20 0.39
NOTUM Q6P988 1/20 0.37
KIF11 P52732 2/20 0.36
CACNA1F O60840 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CACNA1D Q01668 1/20 0.36
CACNA1S Q13698 1/20 0.36
CACNA1C Q13936 1/20 0.36
SOD1 P00441 1/20 0.36
HCAR3 P49019 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
PDE1C Q14123 1/20 0.36
ALOX5 P09917 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28455968 1.00 DDB1 (0.42) DDB1CRBNMGLLNOTUMKIF11
SCHEMBL10210788 0.81 GAA (0.50) DDB1CRBNKIF11PKM
SCHEMBL297089 0.77 KMT2A (0.49)
SCHEMBL17294198 0.74 MAPT (0.46) DDB1CRBNCYP1A2CYP2A6
SCHEMBL7485090 0.74 KDM1A (0.50)
SCHEMBL6385829 0.73 DDB1 (0.55) DDB1CRBNCACNA1FCACNA1DCACNA1S
SCHEMBL25819902 0.72 DDB1 (0.44) DDB1CRBNMGLLNOTUMKIF11
SCHEMBL11017765 0.72 DDB1 (0.44) DDB1CRBN
SCHEMBL1639992 0.72 MAPT (0.48) DDB1CRBNCYP1A2CYP2A6
SCHEMBL11167420 0.71 MAPT (0.45) CACNA1FADORA3CACNA1DCACNA1SCACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0117080-B1 SKIN TREATMENT COMPOSITION UNILEVER PLC (GB) 1992-04-08 EP claimed
EP-0117080-A2 Skin treatment composition UNILEVER PLC (GB) 1984-08-29 EP claimed
US-20250345767-A1 METHODS AND DEVICES FOR GENERATING CORE-SHELL DROPLETS AND PARTICLES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-11-13 US disclosed
US-20240108726-A1 METHODS AND COMPOSITIONS FOR SELF-REGULATED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENT ACURA PHARMACEUTICALS, INC. (US) 2024-04-04 US disclosed
US-11857629-B2 Methods and compositions for self-regulated release of active pharmaceutical ingredient ACURA PHARMACEUTICALS, INC. (US) 2024-01-02 US disclosed
US-20230330044-A1 METHODS AND COMPOSITIONS FOR INTERFERING WITH EXTRACTION OR CONVERSION OF A DRUG SUSCEPTIBLE TO ABUSE ACURA PHARMACEUTICALS INC (US) 2023-10-19 US disclosed
US-11723885-B2 Methods and compositions for interfering with extraction or conversion of a drug susceptible to abuse ACURA PHARMACEUTICALS, INC. (US) 2023-08-15 US disclosed
CN-116367864-A Controlled release filler composition and capsule containing the same R·P·谢勒技术有限公司 2023-06-30 CN disclosed
CN-116322655-A Soft gel capsule for regulating release R·P·谢勒技术有限公司 2023-06-23 CN disclosed
US-20230158008-A1 METHODS AND COMPOSITIONS FOR SELF-REGULATED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENTS ACURA PHARMACEUTICALS, INC. 2023-05-25 US disclosed
US-20230143042-A1 SYSTEM AND METHOD FOR AEROSOL PARTICLE PRODUCTION OF SUBMICRON AND NANO STRUCTURED MATERIALS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2023-05-11 US disclosed
EP-0137343-B1 NOVEL OXOPYRIMIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Taro Pharmaceutical Industries Ltd. (IL) 1991-12-04 EP disclosed
EP-0215027-A4 LIPOSOME IMMUNOASSAY REAGENT AND METHOD. COOPER LIPOTECH INC (US) 1989-06-26 EP disclosed
US-4783400-A Homogeneous enzyme immunoassay system and method COOPER LIPOTECH (US) 1988-11-08 US disclosed
EP-0257640-A2 Vulcanizable elastomer composition NIPPON ZEON CO., LTD. (JP) 1988-03-02 EP disclosed
EP-0215027-A1 LIPOSOME IMMUNOASSAY REAGENT AND METHOD LIPOSOME TECHNOLOGY, INC. (US) 1987-03-25 EP disclosed
US-4628056-A Novel oxopyrimidine derivatives, pharmaceutical compositions containing them and their use as anticonvulsant, antianxiety and muscle relaxant agents TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) 1986-12-09 US disclosed
WO-1986004682-A1 LIPOSOME IMMUNOASSAY REAGENT AND METHOD COOPER-LIPOTECH, INC. (US) 1986-08-14 WO disclosed
US-4458044-A PREVENTION OF FORMATION OF WATER TREES SIEMENS AKTIENGESELLSCHAFT (DE) 1984-07-03 US disclosed
US-3865941-A Therapeutic compositions and method employing 1-morpholinomethyl-5-ethyl-5-phenyl barbituric acid or the hydrochloride salt thereof COLGATE-PALMOLIVE COMPANY, A CORP. OF DE. 1975-02-11 US disclosed