Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364428 | 1.00 | IDH1 (0.31) | IDH1CHRM4RXRAGRIN1GRIN2B | |
| SCHEMBL363791 | 0.84 | AHR (0.37) | MEN1 | |
| SCHEMBL363561 | 0.84 | AHR (0.37) | MEN1 | |
| SCHEMBL15949082 | 0.79 | — | — | |
| SCHEMBL364417 | 0.79 | — | — | |
| SCHEMBL362885 | 0.76 | — | — | |
| SCHEMBL363415 | 0.74 | TLR8 (0.42) | — | |
| SCHEMBL364312 | 0.73 | SMO (0.33) | — | |
| SCHEMBL363169 | 0.72 | CTSA (0.35) | MEN1 | |
| SCHEMBL364479 | 0.72 | CTSA (0.35) | MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |