Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001747 | 0.87 | PTPRZ1 (0.65) | PTPRZ1PTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL95319 | 0.83 | PTPRZ1 (0.61) | PTPRZ1PTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL5537909 | 0.79 | PTPRZ1 (0.57) | PTPRZ1PTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL1161025 | 0.79 | KDM4E (0.59) | PTPRZ1PTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL13064734 | 0.79 | PTPRZ1 (0.57) | PTPRZ1PTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL696549 | 0.79 | PTPRZ1 (0.57) | PTPRZ1PTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL18998006 | 0.78 | PTPRZ1 (0.65) | PTPRZ1PTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL5544527 | 0.76 | PTPRZ1 (0.53) | PTPRZ1PTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL27597569 | 0.76 | PTPRZ1 (0.53) | PTPRZ1PTPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL10655803 | 0.76 | ALDH1A1 (0.52) | PTPRZ1PTPN1ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| EP-2148870-A1 | PYRIMIDINONE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008130584-A1 | PYRIMIDINONE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |