⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653560 | 0.81 | FDPS (0.63) | — | |
| SCHEMBL17396523 | 0.81 | FDPS (0.63) | — | |
| SCHEMBL9111523 | 0.78 | — | — | |
| SCHEMBL9682572 | 0.76 | — | — | |
| SCHEMBL14763893 | 0.76 | — | — | |
| SCHEMBL4095556 | 0.72 | FDPS (1.00) | — | |
| SCHEMBL3889795 | 0.72 | FDPS (0.62) | — | |
| Phosphoric Acid SCHEMBL28238314 | 0.72 | FDPS (0.48) | — | |
| SCHEMBL4536812 | 0.70 | — | — | |
| SCHEMBL2385904 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4422183-B2 | — | — | 2010-02-24 | — | — | JP | claimed |
| EP-1765838-A4 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG LIFE SCIENCES LTD (KR) | 2009-05-27 | — | — | EP | claimed |
| JP-2008505066-A | — | — | 2008-02-21 | — | — | JP | claimed |
| EP-1765838-A1 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG Life Sciences Ltd. (KR) | 2007-03-28 | — | — | EP | claimed |
| WO-2006004330-A1 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG LIFE SCIENCES LTD. (KR) | 2006-01-12 | — | — | WO | claimed |
| US-20090181930-A1 | KINASE INHIBITORY PHOSPHONATE ANALOGS | CANNIZZARO CARINA | 2009-07-16 | — | — | US | disclosed |
| EP-1765838-A4 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG LIFE SCIENCES LTD (KR) | 2009-05-27 | — | — | EP | disclosed |
| US-7417055-B2 | Kinase inhibitory phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| EP-1765838-A1 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG Life Sciences Ltd. (KR) | 2007-03-28 | — | — | EP | disclosed |
| EP-1620109-A2 | KINASE INHIBITOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2006004330-A1 | PROCESS FOR PREPARING DI-ISOPROPYL ((1(HYDROXYMETHYL)-CYCLOPROPYL)OXY) METHYLPHOSPHONATE | LG LIFE SCIENCES LTD. (KR) | 2006-01-12 | — | — | WO | disclosed |
| US-20050261253-A1 | Kinase inhibitory phosphonate analogs | GILEAD SCIENCES, INC. | 2005-11-24 | — | — | US | disclosed |
| WO-2004096234-A2 | KINASE INHIBITOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | disclosed |