SCHEMBL3632062

SCHEMBL3632062

CP(c1ccccc1)c1ccccc1-c1ccccc1P(C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.48
ESR2 Q92731 4/20 0.48
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
DRD1 P21728 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258731 0.89 ESR1 (0.43) ESR1ESR2CYP3A4TDP1
SCHEMBL5810167 0.87 ESR1 (0.54) ESR1ESR2CYP3A4TDP1DRD1
SCHEMBL3962146 0.87 ESR1 (0.54) ESR1ESR2CYP3A4TDP1DRD1
SCHEMBL3790921 0.87 ESR1 (0.42) ESR1ESR2CYP3A4TDP1
SCHEMBL21386422 0.82 ESR1 (0.39) ESR1ESR2
SCHEMBL14101198 0.78 ESR1 (0.46) ESR1ESR2CYP3A4TDP1DRD1
SCHEMBL18573342 0.78 CYP3A4 (0.50) ESR1ESR2CYP3A4TDP1DRD1
SCHEMBL4918290 0.78 ESR1 (0.46) ESR1ESR2CYP3A4TDP1DRD1
SCHEMBL11648324 0.78 ESR1 (0.70) ESR1ESR2CYP3A4TDP1
SCHEMBL40441 0.78 ESR1 (0.70) ESR1ESR2CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3543007-B1 LAMINATE DAIKIN IND LTD (JP) 2023-11-22 EP disclosed
US-7754924-B2 Process for the monosulfonation of aromatic phosphines, and zwitterionic product derived therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-13 US disclosed
US-20080221363-A1 Process for the Monosulfonation of Aromatic Phosphines, and Zwitterionic Product Derived Therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2008-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221363-A1 Process for the Monosulfonation of Aromatic Phosphines, and Zwitterionic Product Derived Therefrom ITK, WEE1, WASF2 ESR1 4115/4885ESR2 4795/4885CYP3A4 3702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.