Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4918290 | 1.00 | ESR1 (0.46) | ESR1ESR2TSHRACHECYP3A4 | |
| SCHEMBL3785328 | 0.98 | ESR1 (0.45) | ESR1ESR2TSHRACHECYP3A4 | |
| SCHEMBL5810167 | 0.85 | ESR1 (0.54) | ESR1ESR2TSHRACHECYP3A4 | |
| SCHEMBL3962146 | 0.85 | ESR1 (0.54) | ESR1ESR2TSHRACHECYP3A4 | |
| SCHEMBL9405363 | 0.85 | TSHR (0.50) | ESR1ESR2TSHRACHECYP3A4 | |
| SCHEMBL15657838 | 0.85 | ESR1 (0.42) | ESR1ESR2TSHRACHECYP3A4 | |
| SCHEMBL8165677 | 0.81 | TSHR (0.41) | ESR1ESR2TSHRACHECYP3A4 | |
| SCHEMBL258915 | 0.80 | ACHE (0.36) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL49618 | 0.78 | CYP3A4 (0.52) | ESR1ESR2TSHRACHECYP3A4 | |
| SCHEMBL3632062 | 0.78 | ESR1 (0.48) | ESR1ESR2CYP3A4TDP1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200407381-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2020-12-31 | — | — | US | disclosed |
| US-9707553-B2 | P-chirogenic organophosphorus compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-07-18 | — | — | US | disclosed |
| US-20160023199-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | SYNTHELOR SAS (FR) | 2016-01-28 | — | — | US | disclosed |
| US-9186661-B2 | P-chirogenic organophosphorus compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-11-17 | — | — | US | disclosed |
| US-20140142325-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS) (FR) | 2014-05-22 | — | — | US | disclosed |
| EP-1577314-B1 | Catalyst based on a transition metal complex for polymerization of olefins, and process for polymerization of olefins using the catalyst | TOSOH CORP (JP) | 2008-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407381-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | PLCG1, PLCG2, ACHE | ESR1 3791/4885ESR2 4047/4885TSHR 3498/4885 |
| US-20160023199-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | ACHE, PTMS, DDT | ESR1 4818/4885ESR2 4771/4885TSHR 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.