Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326781 | 0.89 | MTNR1A (0.49) | MTNR1ANQO2MTNR1BHTR2CHTR2B | |
| SCHEMBL17187860 | 0.81 | CYP1A2 (0.44) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL4584420 | 0.81 | MTNR1A (0.44) | MTNR1ANQO2MTNR1BHTR2CHTR2B | |
| SCHEMBL22967806 | 0.76 | CYP1A2 (0.52) | MTNR1ANQO2MTNR1BHTR2CHTR2B | |
| SCHEMBL12505926 | 0.73 | CYP1A2 (0.48) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL21632076 | 0.72 | KMT2A (0.44) | — | |
| SCHEMBL27401847 | 0.72 | MEN1 (0.46) | — | |
| SCHEMBL28873491 | 0.71 | TRPV1 (0.50) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL18428158 | 0.71 | MTNR1A (0.48) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL3327762 | 0.70 | MTNR1A (0.70) | MTNR1ANQO2MTNR1BHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167457-A2 | NOVEL NAPHTHALENE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009022064-A2 | NOVEL NAPHTHALENE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2009-02-19 | — | — | WO | disclosed |