Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452265 | 0.76 | SLC6A2 (0.51) | SLC6A2MEN1KMT2AKDM4ENQO2 | |
| SCHEMBL8836040 | 0.76 | SLC6A2 (0.51) | SLC6A2MEN1KMT2AKDM4ENQO2 | |
| SCHEMBL3631049 | 0.74 | SLC6A2 (0.50) | SLC6A2MEN1KMT2AKDM4ENQO2 | |
| SCHEMBL3978255 | 0.74 | SLC6A2 (0.50) | SLC6A2MEN1KMT2AKDM4ENQO2 | |
| Hydrochloric Acid SCHEMBL8709005 | 0.73 | SLC6A2 (0.49) | SLC6A2MEN1KMT2AKDM4ENQO2 | |
| SCHEMBL27926787 | 0.72 | SLC6A2 (0.43) | SLC6A2MEN1KMT2AKDM4ENQO2 | |
| SCHEMBL7611582 | 0.72 | SLC6A2 (1.00) | SLC6A2CYP1A2 | |
| SCHEMBL27703610 | 0.72 | SLC6A2 (0.48) | SLC6A2MEN1KMT2AKDM4ENQO2 | |
| SCHEMBL8835800 | 0.71 | SLC6A2 (0.47) | SLC6A2MEN1KMT2AKDM4ENQO2 | |
| SCHEMBL9445636 | 0.71 | SLC6A2 (0.57) | SLC6A2MEN1KMT2AKDM4ENQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142516-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | Sanofi-Aventis (FR) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008121670-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI-AVENTIS (FR) | 2008-10-09 | — | — | WO | disclosed |