Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 5/20 | 0.47 |
| ▸ | HRH1 | P35367 | 5/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958428 | 0.87 | HRH2 (0.47) | HRH2HRH1KITHRH3RAB9A | |
| SCHEMBL3636863 | 0.86 | TP53 (0.44) | HRH2HRH1HRH3RAB9AALDH1A1 | |
| SCHEMBL1692682 | 0.85 | HRH2 (0.48) | HRH2HRH1KITHRH3RAB9A | |
| SCHEMBL14922331 | 0.85 | HRH2 (0.54) | HRH2HRH1KITHRH3RAB9A | |
| SCHEMBL18482713 | 0.84 | HRH2 (0.47) | HRH2HRH1KITHRH3RAB9A | |
| SCHEMBL24664442 | 0.83 | HRH2 (0.49) | HRH2HRH1KITHRH3RAB9A | |
| SCHEMBL10089203 | 0.81 | HRH2 (0.47) | HRH2HRH1KITHRH3RAB9A | |
| SCHEMBL18482715 | 0.81 | HRH2 (0.46) | HRH2HRH1KITHRH3RAB9A | |
| SCHEMBL8921640 | 0.81 | RAB9A (0.45) | HRH2HRH1KITHRH3RAB9A | |
| SCHEMBL1726189 | 0.80 | HRH2 (0.45) | HRH2HRH1KITHRH3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162454-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008150799-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |