Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19417879 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL5509119 | 0.78 | CYP11B1 (0.39) | — | |
| SCHEMBL245979 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL12697280 | 0.75 | GAA (0.46) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL16166710 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL5898755 | 0.74 | IDO1 (0.45) | ALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL3860356 | 0.74 | IDO1 (0.45) | ALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL27756277 | 0.74 | NAPRT (0.49) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9281543 | 0.73 | GAA (0.44) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL3964474 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155735-A2 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008144222-A2 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-11-27 | — | — | WO | disclosed |