Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.60 |
| ▸ | NLN | Q9BYT8 | 3/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18809892 | 0.85 | CYP3A4 (0.67) | CYP3A4SLC7A5NLNHRH4HRH3 | |
| SCHEMBL23974118 | 0.82 | NLN (0.55) | CYP3A4SLC7A5NLNHRH4HRH3 | |
| SCHEMBL11298674 | 0.80 | CYP3A4 (0.52) | CYP3A4SLC7A5NLNHRH4HRH3 | |
| Histidine SCHEMBL27388700 | 0.80 | CYP3A4 (0.88) | CYP3A4SLC7A5NLNHRH4HRH3 | |
| Histidine SCHEMBL29243316 | 0.80 | CYP3A4 (0.88) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL29245588 | 0.77 | CYP3A4 (0.56) | CYP3A4SLC7A5NLNHRH4HRH3 | |
| SCHEMBL7962292 | 0.77 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL13609239 | 0.77 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL18162806 | 0.77 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL18788916 | 0.76 | CYP3A4 (0.55) | CYP3A4SLC7A5NLNHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144921-A2 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | K.U. Leuven Research and Development (BE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008104408-A2 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | K. U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2008-09-04 | — | — | WO | disclosed |