Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.67 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632930 | 0.85 | CYP3A4 (0.60) | CYP3A4SLC7A5NLNHRH4HRH3 | |
| Histidine SCHEMBL27388700 | 0.84 | CYP3A4 (0.88) | CYP3A4SLC7A5NLNHRH4HRH3 | |
| SCHEMBL29245588 | 0.82 | CYP3A4 (0.56) | CYP3A4SLC7A5NLNHRH4HRH3 | |
| SCHEMBL18162806 | 0.82 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL13609239 | 0.82 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL7962292 | 0.82 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL23974118 | 0.81 | NLN (0.55) | CYP3A4SLC7A5NLNHRH4HRH3 | |
| Histidine SCHEMBL28093400 | 0.81 | CYP3A4 (0.93) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| D-Histidine SCHEMBL288043 | 0.80 | CYP3A4 (1.00) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL5497653 | 0.80 | CYP3A4 (0.75) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9974862-B2 | Lipid particles and nucleic acid delivery carrier | FUJIFILM CORPORATION (JP) | 2018-05-22 | — | — | US | disclosed |
| US-20170121714-A1 | METHOD FOR PRODUCING LIPID PARTICLES AND NUCLEIC ACID DELIVERY CARRIER HAVING LIPID PARTICLES | FUJIFILM CORPORATION (JP) | 2017-05-04 | — | — | US | disclosed |
| US-20170119887-A1 | LIPID PARTICLES AND NUCLEIC ACID DELIVERY CARRIER | FUJIFILM CORPORATION (JP) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121714-A1 | METHOD FOR PRODUCING LIPID PARTICLES AND NUCLEIC ACID DELIVERY CARRIER HAVING LIPID PARTICLES | LIPA, LIPC, POLR2H | CYP3A4 2085/4885SLC7A5 1559/4885NLN 2251/4885 |
| US-20170119887-A1 | LIPID PARTICLES AND NUCLEIC ACID DELIVERY CARRIER | NPC1, NPC1L1, LDLR | CYP3A4 4422/4885SLC7A5 178/4885NLN 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.