SCHEMBL3633038

SCHEMBL3633038

[CH2]CCCCOC(=O)/C=C/c1ccc(OC(=O)c2ccc(OCCCC(F)(F)F)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
CYP1A1 P04798 2/20 0.41
CYP1B1 Q16678 2/20 0.41
ESR1 P03372 4/20 0.41
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PPARA Q07869 2/20 0.40
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
AKR1B10 O60218 1/20 0.39
AKR1B1 P15121 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3635015 0.98 ABCG2 (0.42) ABCG2KDM4EMAPTCYP1A1CYP1B1
SCHEMBL3634712 0.97 ABCG2 (0.41) ABCG2KDM4EMAPTCYP1A1CYP1B1
SCHEMBL3693885 0.96 ABCG2 (0.42) ABCG2KDM4EMAPTCYP1A1CYP1B1
SCHEMBL3629575 0.95 LMNA (0.42) ABCG2KDM4EMAPTCYP1A1CYP1B1
SCHEMBL3685127 0.95 ABCG2 (0.41) ABCG2KDM4EMAPTCYP1A1CYP1B1
SCHEMBL3635331 0.94 ABCG2 (0.43) ABCG2KDM4EMAPTCYP1A1CYP1B1
SCHEMBL3634063 0.93 LMNA (0.43) ABCG2KDM4EMAPTCYP1A1CYP1B1
SCHEMBL3634943 0.93 ABCG2 (0.42) ABCG2KDM4EMAPTCYP1A1CYP1B1
SCHEMBL19193813 0.92 ABCG2 (0.44) ABCG2KDM4EMAPTCYP1A1CYP1B1
SCHEMBL3630786 0.92 ABCG2 (0.42) ABCG2KDM4EMAPTCYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2144951-A1 THERMALLY STABLE ALIGNMENT MATERIALS Rolic AG (CH) 2010-01-20 EP disclosed
EP-2142957-A1 METHOD OF UNIFORM AND DEFECT FREE LIQUID CRYSTAL ALIGNING LAYERS Rolic AG (CH) 2010-01-13 EP disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
WO-2008119449-A1 METHOD OF UNIFORM AND DEFECT FREE LIQUID CRYSTAL ALIGNING LAYERS ROLIC AG (CH) 2008-10-09 WO disclosed
EP-1966119-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2008-09-10 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed