Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 12/20 | 0.61 |
| ▸ | BCHE | P06276 | 11/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128053 | 0.98 | ACHE (0.63) | ACHEBCHEHTT | |
| Iodide SCHEMBL10525340 | 0.83 | HTT (0.71) | ACHEBCHEHTT | |
| Iodide SCHEMBL10482575 | 0.83 | HTT (0.71) | ACHEBCHEHTT | |
| SCHEMBL1128086 | 0.81 | HTT (0.73) | ACHEBCHEHTT | |
| Iodide SCHEMBL2447416 | 0.80 | HTT (0.83) | ACHEBCHEHTT | |
| Cadaverine Tartrate SCHEMBL11229118 | 0.80 | MAPT (0.46) | ACHEBCHEHTT | |
| SCHEMBL25613361 | 0.79 | BCHE (0.83) | ACHEBCHE | |
| Bromide SCHEMBL6024510 | 0.79 | BCHE (0.71) | ACHEBCHEHTT | |
| Iodide SCHEMBL10749215 | 0.79 | HTT (0.93) | ACHEBCHEHTT | |
| SCHEMBL1127856 | 0.78 | HTT (0.86) | ACHEBCHEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155684-A1 | PROCESS FOR PRODUCING CISATRACURIUM COMPOUNDS AND ASSOCIATED INTERMEDIATES | Chemagis Ltd. (IL) | 2010-02-24 | — | — | EP | disclosed |
| EP-2142510-A1 | NOVEL ISOQUINOLINIUM COMPOUNDS USEFUL IN THE PREPARATION OF CISATRACURIUM AND ASSOCIATED INTERMEDIATES | Chemagis Ltd. (IL) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008132746-A1 | NOVEL ISOQUINOLINIUM COMPOUNDS USEFUL IN THE PREPARATION OF CISATRACURIUM AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008132748-A1 | PROCESS FOR PRODUCING CISATRACURIUM COMPOUNDS AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2008-11-06 | — | — | WO | disclosed |
| US-4889934-A | Organic mixed complex | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-12-26 | — | — | US | disclosed |
| US-4801713-A | ELECTROCONDUCTIVE COMPLEXES | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-01-31 | — | — | US | disclosed |