Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.78 |
| ▸ | CA2 | P00918 | 3/20 | 0.78 |
| ▸ | CA12 | O43570 | 1/20 | 0.78 |
| ▸ | CA9 | Q16790 | 1/20 | 0.78 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328991 | 0.88 | CA1 (0.74) | CA1CA2CA12CA9POLB | |
| SCHEMBL394902 | 0.85 | CA1 (0.59) | CA1CA2CA12CA9POLB | |
| SCHEMBL9836955 | 0.84 | POLB (0.80) | CA1CA2CA12CA9POLB | |
| SCHEMBL4068451 | 0.82 | POLB (0.78) | CA1CA2CA12CA9POLB | |
| SCHEMBL11800790 | 0.81 | POLB (0.76) | CA1CA2CA12CA9POLB | |
| SCHEMBL10774775 | 0.80 | POLB (0.73) | CA1CA2CA12CA9POLB | |
| SCHEMBL9614881 | 0.79 | POLB (0.84) | CA1CA2CA12CA9POLB | |
| SCHEMBL4824728 | 0.79 | POLB (0.73) | CA1CA2CA12CA9POLB | |
| SCHEMBL7908701 | 0.79 | POLB (0.68) | CA1CA2CA12CA9POLB | |
| SCHEMBL28023600 | 0.78 | ALDH1A1 (0.67) | CA1CA2CA12CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148678-A1 | ANTIVIRAL DRUGS FOR TREATMENT OR PREVENTION OF DENGUE INFECTION | Siga Technologies, Inc. (US) | 2010-02-03 | — | — | EP | claimed |
| WO-2008147962-A1 | ANTIVIRAL DRUGS FOR TREATMENT OR PREVENTION OF DENGUE INFECTION | SIGA TECHNOLOGIES, INC. (US) | 2008-12-04 | — | — | WO | claimed |