Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.60 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317829 | 0.84 | SSTR5 (0.77) | SSTR5KCNH2PTGDR | |
| SCHEMBL10111350 | 0.84 | SSTR5 (0.83) | SSTR5KCNH2PTGDR | |
| SCHEMBL30482791 | 0.83 | SSTR5 (0.72) | SSTR5KCNH2PTGDR | |
| Trifluoroacetic Acid SCHEMBL30482775 | 0.81 | SSTR5 (0.79) | SSTR5KCNH2PTGDR | |
| SCHEMBL25900961 | 0.81 | SSTR5 (0.65) | SSTR5KCNH2PTGDR | |
| SCHEMBL2419405 | 0.81 | SSTR5 (0.61) | SSTR5KCNH2PTGDR | |
| SCHEMBL25314023 | 0.79 | SSTR5 (0.73) | SSTR5KCNH2PTGDR | |
| SCHEMBL10111383 | 0.78 | SSTR5 (0.70) | SSTR5KCNH2PTGDR | |
| SCHEMBL10111398 | 0.78 | SSTR5 (0.70) | SSTR5KCNH2PTGDR | |
| SCHEMBL25314865 | 0.78 | SSTR5 (0.72) | SSTR5KCNH2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152710-A2 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2010-02-17 | — | — | EP | claimed |
| WO-2008145524-A2 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-12-04 | — | — | WO | claimed |