Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2419968 | 0.88 | EGLN1 (0.50) | SSTR5KCNH2PTGDR | |
| SCHEMBL2427785 | 0.85 | EGLN1 (0.51) | SSTR5KCNH2PTGDR | |
| SCHEMBL10111350 | 0.84 | SSTR5 (0.83) | SSTR5KCNH2PTGDR | |
| SCHEMBL2418614 | 0.84 | EGLN1 (0.52) | SSTR5 | |
| SCHEMBL25437832 | 0.84 | SSTR5 (0.77) | SSTR5KCNH2PTGDR | |
| SCHEMBL2418583 | 0.82 | EGLN1 (0.48) | SSTR5KCNH2PTGDR | |
| SCHEMBL14963308 | 0.81 | SSTR5 (0.83) | SSTR5 | |
| SCHEMBL14963304 | 0.81 | SSTR5 (0.84) | SSTR5 | |
| SCHEMBL3633276 | 0.81 | SSTR5 (0.60) | SSTR5KCNH2PTGDR | |
| Trifluoroacetic Acid SCHEMBL30482771 | 0.81 | SSTR5 (0.79) | SSTR5KCNH2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293756-A1 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-11-27 | — | — | US | claimed |
| US-8026365-B2 | 4,4-disubstituted piperidine derivatives | HOFFMAN-LA ROCHE INC. (US) | 2011-09-27 | — | — | US | disclosed |
| US-20080293756-A1 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293756-A1 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | SSTR5, SSTR4, SSTR1 | SSTR5 1/4885KCNH2 811/4885PTGDR 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.