SCHEMBL3633450

SCHEMBL3633450

C[Si](C)(C)CNC1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.39
DPP7 Q9UHL4 2/20 0.38
HRH3 Q9Y5N1 1/20 0.38
USP2 O75604 1/20 0.37
PABPC1 P11940 1/20 0.36
HTT P42858 2/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ANPEP P15144 2/20 0.34
ERAP2 Q6P179 2/20 0.34
RAD52 P43351 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9452259 0.81 KDM4E (0.45) KDM4EALDH1A1HSD17B10DPP7HRH3
SCHEMBL9452442 0.81 KDM4E (0.40) KDM4EALDH1A1HSD17B10DPP7HRH3
SCHEMBL12891509 0.81 KDM4E (0.45) KDM4EALDH1A1HSD17B10DPP7HRH3
SCHEMBL20994264 0.78 OPRL1 (0.37)
SCHEMBL56307 0.78 KDM4E (0.39) KDM4EALDH1A1HSD17B10DPP7USP2
SCHEMBL4776122 0.78 KDM4E (0.39) KDM4EALDH1A1HSD17B10HTTMEN1
SCHEMBL4526083 0.75 KDM4E (0.48) KDM4EALDH1A1HSD17B10DPP7HRH3
SCHEMBL115823 0.75 KDM4E (0.40) KDM4EALDH1A1HSD17B10DPP7HRH3
SCHEMBL123835 0.74 KDM4E (0.35) KDM4EALDH1A1DPP7HRH3USP2
SCHEMBL4449821 0.74 KDM4E (0.35) KDM4EALDH1A1USP2HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4528122-A N-type polyacetylene and a process for producing the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 1985-07-09 US claimed
CN-114867888-A Method for depositing a film 弗萨姆材料美国有限责任公司 2022-08-05 CN disclosed
EP-2148853-A1 INSECTICIDAL ARYL PYRROLIDINES BAYER CROPSCIENCE AG (DE) 2010-02-03 EP disclosed
WO-2008128711-A1 INSECTICIDAL ARYL PYRROLIDINES BAYER CROPSCIENCE AG (DE) 2008-10-30 WO disclosed
US-4528122-A N-type polyacetylene and a process for producing the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 1985-07-09 US disclosed