SCHEMBL56307

SCHEMBL56307

CO[Si](C)(CNC1CCCCC1)OC

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 5/20 0.38
TSHR P16473 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 1/20 0.34
HSD17B10 Q99714 1/20 0.33
EPHX2 P34913 1/20 0.33
USP2 O75604 1/20 0.33
DPP7 Q9UHL4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL628666 0.93 KDM4E (0.35) KDM4EMEN1GAAHTTKMT2A
SCHEMBL1455088 0.87 KDM4E (0.34) KDM4EMEN1GAAHTTKMT2A
SCHEMBL4776122 0.83 KDM4E (0.39) KDM4EMEN1GAAHTTKMT2A
SCHEMBL115823 0.81 KDM4E (0.40) KDM4EMEN1GAAHTTKMT2A
SCHEMBL123835 0.80 KDM4E (0.35) KDM4EMEN1GAAHTTKMT2A
SCHEMBL15360513 0.80 KDM4E (0.40) KDM4EMEN1GAAHTTKMT2A
SCHEMBL18141888 0.79 KDM4E (0.42) KDM4EMEN1GAAHTTKMT2A
SCHEMBL20985092 0.78 ALDH1A1 (0.39) KDM4EMEN1GAAHTTKMT2A
SCHEMBL3633450 0.78 KDM4E (0.43) KDM4EMEN1GAAHTTKMT2A
SCHEMBL773610 0.77 CXCR4 (0.41) KDM4EALDH1A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4700098-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-25 EP claimed
EP-3476876-B1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS MOMENTIVE PERFORMANCE MAT INC (US) 2023-08-09 EP claimed
EP-3212292-B1 POLYMER COMPRISING ALKOXYSILANE GROUPS AND USE IN COSMETICS OREAL (FR) 2021-01-20 EP claimed
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN claimed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US claimed
EP-3476876-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS Momentive Performance Materials Inc. (US) 2019-05-01 EP claimed
EP-3157970-B1 SILYLATED POLYURETHANES HUNTSMAN INT LLC (US) 2019-02-06 EP claimed
US-20170335066-A1 POLYMER COMPRISING ALKOXYSILANE GROUPS AND USE IN COSMETICS L'OREAL (FR) 2017-11-23 US claimed
EP-3212292-A1 POLYMER COMPRISING ALKOXYSILANE GROUPS AND USE IN COSMETICS L'OREAL (FR) 2017-09-06 EP claimed
US-20170198084-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC 2017-07-13 US claimed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP claimed
US-20150166719-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-06-18 US claimed
CN-102186896-B Polyurethane composition that contains alpha-silane and has anisotropic material properties SIKA TECHNOLOGY AG 2014-02-26 CN claimed
CN-102186896-A Polyurethane composition that contains alpha-silane and has anisotropic material properties SIKA TECHNOLOGY AG 2011-09-14 CN claimed
US-20110198030-A1 POLYURETHANE COMPOSITION THAT CONTAINS ALPHA-SILANE AND THAT HAS ANISOTROPIC MATERIAL PROPERTIES SIKA TECHNOLOGY AG (CH) 2011-08-18 US claimed
EP-2189485-B1 Polyurethane composition comprising alpha-silane having anisostropic material properties SIKA TECHNOLOGY AG (CH) 2011-02-16 EP claimed
EP-2189485-A1 Polyurethane composition comprising alpha-silane having anisostropic material properties Sika Technology AG (CH) 2010-05-26 EP claimed
WO-2010049518-A1 POLYURETHANE COMPOSITION THAT CONTAINS ALPHA-SILANE AND HAS ANISOTROPIC MATERIAL PROPERTIES SIKA TECHNOLOGY AG (CH) 2010-05-06 WO claimed
US-7015297-B2 Method of increasing the elasticity of moisture-cured elastomers WACKER-CHEMIE GMBH (DE) 2006-03-21 US claimed
US-20050101753-A1 Method of increasing the elasticity of moisture-cured elastomers WACKER-CHEMIE GMBH (DE) 2005-05-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170335066-A1 POLYMER COMPRISING ALKOXYSILANE GROUPS AND USE IN COSMETICS KRT18, DSG1, KRTCAP2 KDM4E 113/4885MEN1 2498/4885GAA 2505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.