Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550680 | 0.98 | PTGDR2 (0.56) | PTGDR2AKR1B1NAAATDP1CXCL8 | |
| Hydrochloric Acid SCHEMBL11528572 | 0.97 | PTGDR2 (0.55) | PTGDR2AKR1B1NAAATDP1CXCL8 | |
| SCHEMBL7968570 | 0.93 | AKR1B1 (0.53) | PTGDR2AKR1B1TDP1CXCL8PTGS2 | |
| SCHEMBL3107649 | 0.86 | PTGDR2 (0.50) | PTGDR2NAAAPTGS2EPHX2SLC6A2 | |
| SCHEMBL1998542 | 0.85 | PTGDR2 (0.47) | PTGDR2AKR1B1NAAATDP1CXCL8 | |
| SCHEMBL31071979 | 0.85 | AKR1B1 (0.46) | PTGDR2AKR1B1TDP1CXCL8PTGS2 | |
| SCHEMBL12281735 | 0.85 | SLC6A2 (0.57) | AKR1B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21767593 | 0.85 | AKR1B1 (0.46) | PTGDR2AKR1B1TDP1CXCL8PTGS2 | |
| SCHEMBL3979460 | 0.84 | PTGDR2 (0.45) | PTGDR2NAAAEPHX2SLC6A2SLC6A4 | |
| SCHEMBL3983073 | 0.83 | PTGDR2 (0.49) | PTGDR2AKR1B1NAAATDP1CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948164-A1 | PHARMACEUTICAL COMPOSITIONS OF MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2008-07-30 | — | — | EP | claimed |
| WO-2007045979-A1 | PHARMACEUTICAL COMPOSITIONS OF MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | claimed |
| US-10974235-B2 | Targeted, metal-catalyzed fluorination of complex compounds with fluoride ion via decarboxylation | TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200108380-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-04-09 | — | — | US | disclosed |
| US-10543481-B2 | Targeted, metal-catalyzed fluorination of complex compounds with fluoride ion via decarboxylation | TRUSTEES OF PRINCETON UNIVESITY (US) | 2020-01-28 | — | — | US | disclosed |
| US-20180037526-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-02-08 | — | — | US | disclosed |
| EP-3102325-A1 | MOISTURE CURABLE SILICONE COMPOSITION | Momentive Performance Materials Inc. (US) | 2016-12-14 | — | — | EP | disclosed |
| WO-2016130549-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-08-18 | — | — | WO | disclosed |
| US-20160158388-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-06-09 | — | — | US | disclosed |
| WO-2015119904-A1 | MOISTURE CURABLE SILICONE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2015-08-13 | — | — | WO | disclosed |
| WO-2014210492-A1 | MOISTURE CURABLE COMPOSITION WITH STRONTIUM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| US-5637601-A | ANTIPERSPIRANT, MYDRIATIC, ANTISECRETORY AGENTS | UNIVERSITY OF FLORIDA (US) | 1997-06-10 | — | — | US | disclosed |
| US-5618826-A | Anticholinergic compounds, compositions and methods of treatment | UNIVERSITY OF FLORIDA (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| US-5418244-A | Antiperspirants, mydriatic | UNIVERSITY OF FLORIDA (US) | 1995-05-23 | — | — | US | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |
| US-5223528-A | Antisecretory agents, mydriatics, antiperspirants | UNIVERSITY OF FLORIDA (US) | 1993-06-29 | — | — | US | disclosed |
| US-5034429-A | An unsaturated monomer, a photoinitiator and a benzene derivative for providing a cured film | HITACHI CHEMICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0143978-B1 | PROCESS FOR MAKING LOW CRYSTALLINITY POLYOLEFINS | HERCULES INCORPORATED (US) | 1988-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158388-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | AFF2, CLTC, AFF4 | PTGDR2 4202/4885AKR1B1 3587/4885NAAA 352/4885 |
| US-10543481-B2 | Targeted, metal-catalyzed fluorination of complex compounds with fluoride ion via decarboxylation | AFF2, CLTC, AFF4 | PTGDR2 4202/4885AKR1B1 3587/4885NAAA 352/4885 |
| US-20180037526-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | AFF2, CLTC, AFF4 | PTGDR2 4202/4885AKR1B1 3587/4885NAAA 352/4885 |
| US-10974235-B2 | Targeted, metal-catalyzed fluorination of complex compounds with fluoride ion via decarboxylation | AFF2, CLTC, AFF4 | PTGDR2 4202/4885AKR1B1 3587/4885NAAA 352/4885 |
| US-20200108380-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | AFF2, CLTC, AFF4 | PTGDR2 4202/4885AKR1B1 3587/4885NAAA 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.