SCHEMBL3633574

SCHEMBL3633574

COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1ncc(C)c(C)n1

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA9 Q16790 3/20 0.47
CA5A P35218 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
NPC1 O15118 2/20 0.46
GAA P10253 1/20 0.46
CA12 O43570 1/20 0.45
SLC40A1 Q9NP59 1/20 0.45
BRD4 O60885 1/20 0.44
FBP1 P09467 1/20 0.43
MAPT P10636 1/20 0.43
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11076843 0.89 NPC1 (0.46) CA1CA2CA9CA5AMEN1
SCHEMBL11069439 0.88 NPC1 (0.46) CA1CA2CA9CA5AMEN1
SCHEMBL11057471 0.86 NPC1 (0.50) CA1CA2CA9CA5AMEN1
SCHEMBL10665567 0.86 CYP3A4 (0.43) CA1CA2CA9MEN1KMT2A
SCHEMBL10507288 0.84 NPC1 (0.48) CA1CA2CA9CA5AMEN1
SCHEMBL11076663 0.84 NPC1 (0.48) CA1CA2CA9CA5AMEN1
SCHEMBL11051029 0.84 NPC1 (0.48) CA1CA2CA9CA5AMEN1
SCHEMBL11076508 0.84 NPC1 (0.48) CA1CA2CA9CA5AMEN1
Monosulfuron Ester SCHEMBL27573934 0.83 SLC40A1 (0.48) CA1CA2CA9CA5AMEN1
SCHEMBL9727134 0.83 CA1 (0.48) CA1CA2CA9CA5AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2160427-A1 GRANULE COATED WITH URETHANE RESIN Sumitomo Chemical Company, Limited (JP) 2010-03-10 EP disclosed
WO-2009001477-A1 GRANULE COATED WITH URETHANE RESIN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-12-31 WO disclosed
US-20050112571-A1 Dna molecules conferring tolerance to herbicidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2005-05-26 US disclosed
EP-1414982-A2 DNA MOLECULES ENCODING HERBICIDE TOLERANT ACETOLACTATE SYNTHASE Syngenta Participations AG (CH) 2004-05-06 EP disclosed
WO-2003012115-A2 DNA MOLECULES ENCODING HERBICIDE TOLERANT ACETOLACTATE SYNTHASE SYNGENTA PARTICIPATIONS AG (CH) 2003-02-13 WO disclosed
US-6159900-A Synergistic herbicidal agents HOECHST AKTIENGESELLSCHAFT (DE) 2000-12-12 US disclosed
US-5635448-A 3-SUBSTITUTED PHENYLPYRAZOLE DERIVATIVES ASAMURA PATENT OFFICE (JP) 1997-06-03 US disclosed
EP-0619946-B1 Herbicidal composition for upland farming and weeding method NIHON NOHYAKU CO LTD (JP) 1996-06-05 EP disclosed
EP-0619946-A1 Herbicidal composition for upland farming and weeding method NIHON NOHYAKU CO., LTD. (JP) 1994-10-19 EP disclosed