Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 18/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2346840 | 1.00 | UTS2R (0.59) | UTS2RDRD2DRD4DRD3 | |
| SCHEMBL2346047 | 0.92 | UTS2R (0.68) | UTS2R | |
| SCHEMBL2346051 | 0.88 | UTS2R (0.65) | UTS2R | |
| SCHEMBL3633753 | 0.88 | UTS2R (0.66) | UTS2R | |
| SCHEMBL2341376 | 0.88 | UTS2R (0.66) | UTS2R | |
| SCHEMBL2341777 | 0.85 | UTS2R (0.65) | UTS2R | |
| SCHEMBL2349470 | 0.85 | UTS2R (0.68) | UTS2R | |
| SCHEMBL12157486 | 0.83 | UTS2R (0.64) | UTS2R | |
| SCHEMBL2351169 | 0.82 | UTS2R (0.69) | UTS2R | |
| SCHEMBL2351051 | 0.82 | UTS2R (0.70) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161994-A2 | UROTENSIN II RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008153902-A2 | UROTENSIN II RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-12-18 | — | — | WO | disclosed |