Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633855 | 0.82 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL25510873 | 0.81 | TRPV1 (0.60) | TRPV1 | |
| SCHEMBL2163326 | 0.80 | TRPV1 (0.59) | TRPV1 | |
| SCHEMBL29769771 | 0.80 | TRPV1 (0.59) | TRPV1 | |
| Hydrochloric Acid SCHEMBL14659282 | 0.79 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL2526749 | 0.78 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL3633856 | 0.78 | TRPV1 (0.71) | TRPV1 | |
| SCHEMBL3633925 | 0.76 | TRPV1 (0.75) | TRPV1 | |
| SCHEMBL2162453 | 0.75 | TRPV1 (0.86) | TRPV1 | |
| SCHEMBL14659322 | 0.74 | TRPV1 (0.71) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103917523-A | Amine-substituted methanesulfonamide derivatives as vanilloid receptor ligands | GRUENENTHAL GMBH | 2014-07-09 | — | — | CN | disclosed |
| EP-2150531-A2 | NOVEL VANILLOID RECEPTOR LIGANDS, AND THEIR USE FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008125295-A2 | NOVEL VANILLOID RECEPTOR LIGANDS, AND THEIR USE FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2008-10-23 | — | — | WO | disclosed |