Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887568 | 0.91 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL4887552 | 0.91 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL3634591 | 0.90 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL3634588 | 0.90 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL3668946 | 0.86 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL3640438 | 0.86 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL3636140 | 0.85 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL3636147 | 0.85 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL3639933 | 0.84 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL3669380 | 0.83 | AGTR1 (0.69) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162442-A1 | DUAL-ACTING BENZOIMIDAZOLE ANTIHYPERTENSIVE AGENTS | Theravance, Inc. (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008153857-A1 | DUAL-ACTING BENZOIMIDAZOLE ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2008-12-18 | — | — | WO | disclosed |