SCHEMBL3634628

SCHEMBL3634628

N#Cc1ccc2c(Br)cc3c4ccccc4c(Br)cc3c2c1.N#Cc1ccc2ccc3c4ccccc4ccc3c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
HPRT1 P00492 4/20 0.44
CYP1B1 Q16678 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP1A1 P04798 1/20 0.41
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 2/20 0.41
HIF1A Q16665 1/20 0.41
ANPEP P15144 1/20 0.40
KDM4E B2RXH2 2/20 0.39
PTPN1 P18031 2/20 0.38
PTPN2 P17706 1/20 0.38
CYP2A6 P11509 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PDPK1 O15530 1/20 0.38
CYP2C19 P33261 2/20 0.37
CYP2D6 P10635 1/20 0.37
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634282 0.90 CA1 (0.44) CA1CA2ALDH1A1KDM4EPTPN1
SCHEMBL3632654 0.88 CA1 (0.65) CA1CA2HPRT1CYP1B1CYP1A2
SCHEMBL29131409 0.88 CA1 (0.65) CA1CA2HPRT1CYP1B1CYP1A2
SCHEMBL1343465 0.85 CA1 (0.69) CA1CA2HPRT1CYP1B1CYP1A2
SCHEMBL2128868 0.83 HPRT1 (0.64) HPRT1CYP1B1CYP1A2CYP1A1ALDH1A1
SCHEMBL1093414 0.83 HPRT1 (0.64) HPRT1CYP1B1CYP1A2CYP1A1ALDH1A1
SCHEMBL12310187 0.81 CA1 (0.65) CA1CA2HPRT1CYP1B1CYP1A2
SCHEMBL12320895 0.81 CA1 (0.65) CA1CA2HPRT1CYP1B1CYP1A2
SCHEMBL1344052 0.79 CA1 (0.67) CA1CA2HPRT1CYP1B1CYP1A2
SCHEMBL18934329 0.79 CA1 (0.53) CA1CA2ALDH1A1KDM4ECYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2150599-A1 CHRYSENES FOR GREEN LUMINESCENT APPLICATIONS E. I. Du Pont de Nemours and Company (US) 2010-02-10 EP disclosed
WO-2008150940-A1 CHRYSENES FOR GREEN LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-11 WO disclosed