SCHEMBL3634282

SCHEMBL3634282

N#Cc1ccc2c(Br)cc3c4ccccc4c(Br)cc3c2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
AR P10275 1/20 0.38
TSHR P16473 1/20 0.38
CXCR2 P25025 2/20 0.38
CXCR1 P25024 1/20 0.38
G6PD P11413 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TTR P02766 1/20 0.36
ALB P02768 1/20 0.36
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
TNKS O95271 1/20 0.34
PTPN1 P18031 2/20 0.34
PTPN2 P17706 1/20 0.34
FASN P49327 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634628 0.90 CA1 (0.53) CA1CA2TSHRKDM4EALDH1A1
SCHEMBL18934329 0.88 CA1 (0.53) CA1CA2ARTSHRG6PD
SCHEMBL16940478 0.85 CA1 (0.44) CA1CA2ARTSHRCXCR2
SCHEMBL22155103 0.82 TNKS (0.40) CA1CA2TSHRMEN1KMT2A
SCHEMBL13074276 0.81 CA2 (0.43) CA1CA2ARTSHRMEN1
SCHEMBL31533202 0.78 ALDH1A1 (0.43) TSHRMEN1KMT2AKDM4EALDH1A1
SCHEMBL349252 0.78 ALDH1A1 (0.43) TSHRMEN1KMT2AKDM4EALDH1A1
SCHEMBL29558067 0.78 ALDH1A1 (0.43) TSHRMEN1KMT2AKDM4EALDH1A1
SCHEMBL18852194 0.77 ALDH1A1 (0.50) CA1CA2ARTSHRG6PD
Methane SCHEMBL28982422 0.76 ALDH1A1 (0.42) MEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2150599-A1 CHRYSENES FOR GREEN LUMINESCENT APPLICATIONS E. I. Du Pont de Nemours and Company (US) 2010-02-10 EP disclosed
WO-2008150940-A1 CHRYSENES FOR GREEN LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-11 WO disclosed
US-20080303428-A1 CHRYSENES FOR GREEN LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080303428-A1 CHRYSENES FOR GREEN LUMINESCENT APPLICATIONS CRY2, CENPE, CRY1 CA1 2272/4885CA2 884/4885AR 3282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.