Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 16/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693265 | 0.91 | CCR1 (0.44) | CCR1ALKMAPTCYP2C19KCNH2 | |
| SCHEMBL3635666 | 0.86 | CCR1 (0.50) | CCR1ALKMAPT | |
| SCHEMBL3632118 | 0.86 | CCR1 (0.41) | CCR1ALKMAPT | |
| SCHEMBL3637059 | 0.84 | CCR1 (0.49) | CCR1ALKMAPTCYP2C19KCNH2 | |
| SCHEMBL2354678 | 0.84 | CCR1 (0.48) | CCR1ALKMAPT | |
| SCHEMBL3640142 | 0.84 | CCR1 (0.48) | CCR1ALKMAPTCYP2C19KCNH2 | |
| SCHEMBL4694944 | 0.83 | CCR1 (0.41) | CCR1ALK | |
| SCHEMBL4696966 | 0.82 | CCR1 (0.51) | CCR1ALKMAPT | |
| SCHEMBL4751086 | 0.81 | CCR1 (0.46) | CCR1ALKMAPTCYP2C19KCNH2 | |
| SCHEMBL3635896 | 0.81 | CCR1 (0.48) | CCR1ALKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155203-A1 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | ChemoCentryx Inc (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008147822-A1 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2008-12-04 | — | — | WO | disclosed |