Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 13/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637368 | 0.87 | CCR1 (0.41) | CCR1SUV39H2 | |
| SCHEMBL3636906 | 0.86 | CCR1 (0.42) | CCR1ALKRXRAGRIN1GRIN2B | |
| SCHEMBL3632624 | 0.86 | CCR1 (0.43) | CCR1 | |
| SCHEMBL4317440 | 0.86 | CCR1 (0.42) | CCR1SUV39H2BRD4 | |
| SCHEMBL3636075 | 0.85 | ALDH1A1 (0.36) | ALKSUV39H2 | |
| SCHEMBL3637478 | 0.84 | CCR1 (0.39) | CCR1BRD4 | |
| SCHEMBL3634696 | 0.83 | CCR1 (0.46) | CCR1ALK | |
| SCHEMBL4692528 | 0.82 | CCR1 (0.40) | CCR1 | |
| SCHEMBL3639609 | 0.82 | CCR1 (0.40) | CCR1SUV39H2BRD4 | |
| SCHEMBL4693265 | 0.81 | CCR1 (0.44) | CCR1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1906965-A2 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | ChemoCentryx Inc (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007002293-A2 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-01-04 | — | — | WO | disclosed |