Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672061 | 0.93 | TSHR (0.54) | TP53CRHBPCRHR2L3MBTL1TDP1 | |
| SCHEMBL12506256 | 0.88 | HTR2A (0.56) | TDP1HTR2AHRH1LMNATAAR1 | |
| SCHEMBL15347956 | 0.86 | HTR2A (0.53) | TDP1HTR2AHRH1LMNAOPRM1 | |
| SCHEMBL54346 | 0.85 | HTR2A (0.59) | TDP1HTR2AHRH1LMNATAAR1 | |
| SCHEMBL6547305 | 0.84 | ATM (0.47) | TP53CRHBPCRHR2L3MBTL1TDP1 | |
| SCHEMBL6895362 | 0.84 | CALM1 (0.52) | TP53TDP1HTR2AHRH1LMNA | |
| SCHEMBL14361867 | 0.84 | TP53 (0.59) | TP53CRHBPCRHR2L3MBTL1TDP1 | |
| Ammonia Solution, Strong SCHEMBL10389261 | 0.83 | HTR2A (0.56) | TDP1TSHRHTR2AHRH1LMNA | |
| SCHEMBL29268835 | 0.83 | HTR2A (0.56) | TDP1TSHRHTR2AHRH1LMNA | |
| Ammonia Solution, Strong SCHEMBL5683105 | 0.83 | HTR2A (0.56) | TDP1TSHRHTR2AHRH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158233-A2 | ADDUCTS, ADDUCTS AND OLIGOMERS, OR ADDUCTS, OLIGOMERS AND LOW MOLECULAR WEIGHT POLYMERS, AND THEIR PREPARATION | Albermarle Corporation (US) | 2010-03-03 | — | — | EP | disclosed |
| WO-2008154454-A2 | ADDUCTS, ADDUCTS AND OLIGOMERS, OR ADDUCTS, OLIGOMERS AND LOW MOLECULAR WEIGHT POLYMERS, AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| CN-1040321-C | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses | UPJOHN CO (US) | 1998-10-21 | — | — | CN | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |