Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635090 | 0.85 | NPY1R (0.47) | NPY1RNPY2RPOLBPTGDR2PDE4B | |
| SCHEMBL3632974 | 0.83 | NPY1R (0.54) | NPY1RNPY2RPOLBCSNK2A1PTGDR | |
| SCHEMBL25371685 | 0.80 | NPY1R (0.60) | NPY1RNPY2RCSNK2A1PTGDRPTGDR2 | |
| SCHEMBL30694792 | 0.80 | NPY1R (0.60) | NPY1RNPY2RCSNK2A1PTGDRPTGDR2 | |
| SCHEMBL27778858 | 0.77 | NPY1R (0.54) | NPY1RNPY2RPOLBCSNK2A1PTGDR | |
| SCHEMBL25369504 | 0.77 | NPY1R (0.57) | NPY1RNPY2RCSNK2A1PTGDRPTGDR2 | |
| SCHEMBL18003630 | 0.75 | POLB (0.49) | NPY1RNPY2RPOLBPTGDR2PDE4B | |
| SCHEMBL1821904 | 0.74 | KDM4E (0.51) | POLBMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL18809057 | 0.72 | NPY1R (0.55) | NPY1RNPY2RPOLBPDE4BPDE4A | |
| SCHEMBL16935329 | 0.71 | POLB (0.40) | NPY1RNPY2RPOLBCSNK2A1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152699-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008150029-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-12-11 | — | — | WO | disclosed |