Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.60 |
| ▸ | NPY2R | P49146 | 1/20 | 0.60 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25371685 | 1.00 | NPY1R (0.60) | NPY1RNPY2RPTGDR2CSNK2A1NPC1 | |
| SCHEMBL25369504 | 0.97 | NPY1R (0.57) | NPY1RNPY2RPTGDR2CSNK2A1NPC1 | |
| SCHEMBL4585924 | 0.86 | NPY1R (0.49) | NPY1RNPY2RPTGDR2CSNK2A1NPC1 | |
| SCHEMBL27778858 | 0.81 | NPY1R (0.54) | NPY1RNPY2RPTGDR2CSNK2A1PTGDR | |
| SCHEMBL3632974 | 0.81 | NPY1R (0.54) | NPY1RNPY2RPTGDR2CSNK2A1NPC1 | |
| SCHEMBL18584829 | 0.81 | MAPT (0.49) | NPY1RNPY2RPTGDR2CSNK2A1PTGDR | |
| SCHEMBL3635560 | 0.80 | NPY1R (0.56) | NPY1RNPY2RPTGDR2CSNK2A1PTGDR | |
| SCHEMBL29333349 | 0.80 | NPY1R (0.43) | NPY1RNPY2RPTGDR2 | |
| SCHEMBL14786273 | 0.77 | MAPT (0.49) | NPY1RNPY2RCSNK2A1PTGDRMAPT | |
| SCHEMBL25370223 | 0.77 | NPY1R (0.39) | NPY1RNPY2RCSNK2A1RECQLPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295736-A | Benzo [ C ] [2,6] naphthyridine derivatives, compositions thereof and therapeutic uses thereof | 剑桥实业有限公司 | 2023-12-26 | — | — | CN | disclosed |