Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 10/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60343 | 1.00 | EPHX1 (0.47) | EPHX1GBA1ACHETNFTLR4 | |
| SCHEMBL236414 | 1.00 | EPHX1 (0.47) | EPHX1GBA1ACHETNFTLR4 | |
| SCHEMBL8820095 | 0.94 | EPHX1 (0.42) | EPHX1GBA1ACHETNFTLR4 | |
| SCHEMBL8820100 | 0.94 | EPHX1 (0.42) | EPHX1GBA1ACHETNFTLR4 | |
| SCHEMBL5276297 | 0.89 | EPHX1 (0.42) | EPHX1ACHETLR4ADORA1 | |
| SCHEMBL1857528 | 0.87 | EPHX1 (0.47) | EPHX1ACHETLR4ADORA1 | |
| SCHEMBL3635578 | 0.84 | TLR4 (0.50) | EPHX1ACHETLR4 | |
| SCHEMBL60345 | 0.84 | TLR4 (0.50) | EPHX1ACHETLR4 | |
| SCHEMBL15870614 | 0.84 | TLR4 (0.50) | EPHX1ACHETLR4 | |
| SCHEMBL60344 | 0.84 | TLR4 (0.50) | EPHX1ACHETLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100330596-A1 | LIPOPROTEIN SURFACTANT | ROCHE DIABETES CARE, INC. | 2010-12-30 | — | — | US | claimed |
| EP-2164982-A2 | LIPOPROTEIN SURFACTANT | F.HOFFMANN-LA ROCHE AG (CH) | 2010-03-24 | — | — | EP | claimed |
| WO-2008152380-A2 | LIPOPROTEIN SURFACTANT | OXFORD BIOSENSORS LIMITED (GB) | 2008-12-18 | — | — | WO | claimed |
| US-20100330596-A1 | LIPOPROTEIN SURFACTANT | ROCHE DIABETES CARE, INC. | 2010-12-30 | — | — | US | disclosed |
| EP-2164982-A2 | LIPOPROTEIN SURFACTANT | F.HOFFMANN-LA ROCHE AG (CH) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008152380-A2 | LIPOPROTEIN SURFACTANT | OXFORD BIOSENSORS LIMITED (GB) | 2008-12-18 | — | — | WO | disclosed |
| EP-1656443-A4 | SOLID PHASE CELL LYSIS AND CAPTURE PLATFORM | SIGMA ALDRICH CO (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1656443-A2 | SOLID PHASE CELL LYSIS AND CAPTURE PLATFORM | Sigma-Aldrich Co. (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2004099384-A2 | SOLID PHASE CELL LYSIS AND CAPTURE PLATFORM | SIGMA-ALDRICH CO. (US) | 2004-11-18 | — | — | WO | disclosed |