Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 7/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635578 | 1.00 | TLR4 (0.50) | TLR4EPHX1ACHEPRKACAAKT1 | |
| SCHEMBL15870614 | 1.00 | TLR4 (0.50) | TLR4EPHX1ACHEPRKACAAKT1 | |
| SCHEMBL18976840 | 1.00 | TLR4 (0.50) | TLR4EPHX1ACHEPRKACAAKT1 | |
| SCHEMBL60345 | 1.00 | TLR4 (0.50) | TLR4EPHX1ACHEPRKACAAKT1 | |
| Urethane SCHEMBL3737671 | 0.92 | TLR4 (0.44) | TLR4EPHX1ACHEPRKACA | |
| SCHEMBL2279209 | 0.88 | TLR4 (0.48) | TLR4EPHX1AKT1 | |
| SCHEMBL1857528 | 0.86 | EPHX1 (0.47) | TLR4EPHX1ACHE | |
| SCHEMBL3635575 | 0.84 | EPHX1 (0.47) | TLR4EPHX1ACHE | |
| SCHEMBL60343 | 0.84 | EPHX1 (0.47) | TLR4EPHX1ACHE | |
| SCHEMBL236414 | 0.84 | EPHX1 (0.47) | TLR4EPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112618700-A | Stable formulations of insulinotropic peptides | 诺和诺德公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-106137952-B | Stable formulations of insulinotropic peptides | 诺和诺德公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-105832658-B | Stable formulations of insulinotropic peptides | 诺和诺德公司 | 2020-07-31 | — | — | CN | disclosed |
| EP-2494983-B1 | STABLE FORMULATIONS OF GLP-1 | NOVO NORDISK AS (DK) | 2019-04-24 | — | — | EP | disclosed |
| EP-2190872-B1 | GLUCAGON-LIKE PEPTIDE-1 DERIVATIVES AND THEIR PHARMACEUTICAL USE | NOVO NORDISK AS (DK) | 2018-03-14 | — | — | EP | disclosed |
| US-9657079-B2 | Truncated GLP-1 derivatives and their therapeutical use | NOVO NORDISK A/S (DK) | 2017-05-23 | — | — | US | disclosed |
| US-9409966-B2 | Glucagon-like peptide-1 derivatives and their pharmaceutical use | NOVO NORDISK A/S (DK) | 2016-08-09 | — | — | US | disclosed |
| EP-1814581-B1 | STABLE FORMULATIONS OF PEPTIDES COMPRISING AN ACYLATED GLP-1 ANALOGUE AND A BASAL INSULINE | NOVO NORDISK AS (DK) | 2016-03-16 | — | — | EP | disclosed |
| CN-101133082-B | ACYLATED GLP-1 COMPOUNDS | NOVO NORDISK A/S (DK) | 2016-01-13 | — | — | CN | disclosed |
| EP-2322546-B1 | Acylated GLP-1 compounds | NOVO NORDISK AS (DK) | 2015-09-30 | — | — | EP | disclosed |
| CN-101133082-A | Acylated GLP-1 compounds | NOVO NORDISK AS (DK) | 2008-02-27 | — | — | CN | disclosed |
| WO-2007135118-A1 | SOLUBLE, STABLE INSULIN-CONTAINING FORMULATIONS | NOVO NORDISK A/S (DK) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007135117-A2 | SOLUBLE, STABLE INSULIN-CONTAINING FORMULATIONS | NOVO NORDISK A/S (DK) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007104786-A1 | MIXTURES OF AMYLIN AND INSULIN | NOVO NORDISK A/S (DK) | 2007-09-20 | — | — | WO | disclosed |
| EP-1817048-A2 | STABLE FORMULATIONS OF INSULINOPTROPIC PEPTIDES | NOVO NORDISK A/S (DK) | 2007-08-15 | — | — | EP | disclosed |
| EP-1817049-A1 | SOLUBLE, STABLE INSULIN-CONTAINING FORMULATIONS WITH A PROTAMINE SALT | NOVO NORDISK A/S (DK) | 2007-08-15 | — | — | EP | disclosed |
| EP-1814581-A2 | STABLE FORMULATIONS OF PEPTIDES | NOVO NORDISK A/S (DK) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006053906-A1 | SOLUBLE, STABLE INSULIN-CONTAINING FORMULATIONS WITH A PROTAMINE SALT | NOVO NORDISK A/S (DK) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006051110-A2 | STABLE FORMULATIONS OF INSULINOPTROPIC PEPTIDES | NOVO NORDISK A/S (DK) | 2006-05-18 | — | — | WO | disclosed |
| WO-2006051103-A2 | STABLE FORMULATIONS OF PEPTIDES | NOVO NORDISK A/S (DK) | 2006-05-18 | — | — | WO | disclosed |