Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.64 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3089050 | 0.89 | MET (0.60) | METHDAC1 | |
| SCHEMBL16192669 | 0.85 | MET (0.49) | METNQO2 | |
| SCHEMBL3099598 | 0.85 | MET (0.87) | METNQO2 | |
| SCHEMBL3637061 | 0.84 | MET (0.60) | METNQO2 | |
| SCHEMBL13152366 | 0.84 | MET (0.63) | METHDAC1 | |
| SCHEMBL3634828 | 0.84 | MET (0.65) | METNQO2HDAC1 | |
| SCHEMBL13152404 | 0.84 | MET (0.62) | METHDAC1 | |
| SCHEMBL3081923 | 0.83 | MET (0.59) | METHDAC1 | |
| SCHEMBL3636278 | 0.82 | MET (0.61) | METNQO2 | |
| SCHEMBL16192837 | 0.81 | MET (0.67) | METNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2754660-B1 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-11-02 | — | — | EP | claimed |
| EP-2164843-B1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2014-10-29 | — | — | EP | claimed |
| EP-2754660-B1 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-2164843-B1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2014-10-29 | — | — | EP | disclosed |
| EP-2164843-A1 | PYRIDAZINONE DERIVATES | Merck Patent GmbH (DE) | 2010-03-24 | — | — | EP | disclosed |
| WO-2009006959-A1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2009-01-15 | — | — | WO | disclosed |