Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635129 | 0.95 | GRM2 (0.41) | GRM2SIGMAR1CCR8 | |
| SCHEMBL3634046 | 0.93 | GRM2 (0.39) | GRM2SIGMAR1CCR8TP53MAPT | |
| SCHEMBL3635685 | 0.88 | GRM2 (0.42) | GRM2SIGMAR1 | |
| SCHEMBL3633217 | 0.83 | KCNH2 (0.35) | CCR8 | |
| SCHEMBL3634955 | 0.81 | MAOA (0.36) | CCR8 | |
| SCHEMBL1224602 | 0.74 | GRM2 (0.40) | GRM2SIGMAR1POLB | |
| SCHEMBL1224604 | 0.74 | GRM2 (0.40) | GRM2SIGMAR1POLB | |
| SCHEMBL1222987 | 0.74 | GRM2 (0.39) | GRM2SIGMAR1POLB | |
| SCHEMBL1223674 | 0.74 | GRM2 (0.39) | GRM2SIGMAR1POLB | |
| SCHEMBL1223188 | 0.71 | GRM2 (0.41) | GRM2CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144910-A2 | OXAZOLIDINONE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008126034-A2 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |