Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708142 | 0.79 | TDP1 (0.36) | SMN1; SMN2 | |
| SCHEMBL8642646 | 0.76 | GABRR1 (0.35) | LMNASMN1; SMN2 | |
| SCHEMBL4653097 | 0.76 | LMNA (0.35) | MAPTLMNAUSP2CYP3A4RECQL | |
| SCHEMBL5451680 | 0.73 | MAPT (0.39) | MAPTABCC4LMNAUSP2CYP3A4 | |
| SCHEMBL18093429 | 0.72 | MAPT (0.40) | MAPTABCC4LMNAUSP2CYP3A4 | |
| SCHEMBL18093427 | 0.72 | MAPT (0.40) | MAPTABCC4LMNAUSP2CYP3A4 | |
| SCHEMBL5435517 | 0.72 | TSHR (0.33) | MAPTLMNAUSP2CYP3A4RECQL | |
| SCHEMBL875951 | 0.69 | MAPT (0.38) | MAPTLMNAUSP2CYP3A4RECQL | |
| SCHEMBL30621793 | 0.69 | MAPT (0.40) | MAPTABCC4LMNAUSP2CYP3A4 | |
| SCHEMBL29119349 | 0.69 | F7 (0.44) | MAPTLMNAUSP2CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160442-A1 | PRIMER FOR COMPOSITE BUILDING MATERIALS | James Hardie International Finance B.V. (NL) | 2010-03-10 | — | — | EP | disclosed |
| WO-2009006304-A1 | PRIMER FOR COMPOSITE BUILDING MATERIALS | JAMES HARDIE INTERNATIONAL FINANCE B.V. (NL) | 2009-01-08 | — | — | WO | disclosed |
| US-20090004468-A1 | PRIMER FOR COMPOSITE BUILDING MATERIALS | James Hardie Technology Limited (IE) | 2009-01-01 | — | — | US | disclosed |