SCHEMBL3635910

SCHEMBL3635910

COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2C(CNC(=O)[C@H]2CNCCN2)c2c[nH]c3ccccc23)cc1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3635909 0.86 GHSR (0.85) GHSR
SCHEMBL13018953 0.86 GHSR (0.85) GHSR
SCHEMBL3729255 0.86 GHSR (0.85) GHSR
SCHEMBL20525917 0.84 GHSR (0.68) GHSR
SCHEMBL3672599 0.83 GHSR (0.83) GHSR
SCHEMBL13018951 0.83 GHSR (0.83) GHSR
SCHEMBL4113393 0.83 GHSR (0.83) GHSR
SCHEMBL3672601 0.83 GHSR (0.83) GHSR
SCHEMBL20525990 0.83 GHSR (0.77) GHSR
SCHEMBL3635889 0.83 GHSR (0.80) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155227-A1 NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION Dickson, Suzanne L (SE) 2010-02-24 — — EP disclosed
WO-2009020419-A1 NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION DICKSON SUZANNE L (SE) 2009-02-12 — — WO disclosed
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